Neuromodulation is the second-oldest and third-largest Medtronic business unit. It was formed as we transferred our expertise in heart electrical stimulation to treat diseases and conditions involving the nervous system. Today, our products include neurostimulation systems and implantable drug delivery systems for chronic pain, common movement disorders, psychiatric disorders, and urologic and gastrointestinal disorders.

Key Product Categories

Deep Brain Stimulation (DBS) Systems

Deep Brain Stimulation Therapy

DBS Therapy is a treatment for movement symptoms of Parkinson’s disease, essential tremor, and dystonia,* and for symptoms of obsessive-compulsive disorder.* During DBS Therapy, a small, pacemaker-like device sends electronic signals to a precisely targeted area of the brain, blocking signals that cause symptoms.


Parkinson's disease, essential tremor, dystonia*

Obsessive-compulsive disorder (OCD)*

* The Medtronic Therapy for this disorder is available through a Humanitarian Device Exemption in the United States. The effectiveness of the therapy for this disorder has not been demonstrated.

Targeted Drug Delivery Systems

Drug Infusion system to manage chronic pain

Medtronic Targeted Drug Delivery uses a system, consisting of an implanted drug infusion pump and catheter and an external clinician programmer, to deliver precise amounts of medication directly to the fluid surrounding the spinal cord (known as the intrathecal space) for potential symptom relief with less medication than conventional oral medications. Thus, Targeted Drug Delivery offers alternate route of drug delivery for patients who do not respond to or cannot tolerate therapeutic oral doses.

Medtronic drug delivery systems are used to manage severe spasticity and chronic pain of malignant or non-malignant origin.


Cancer Pain

Chronic pain

Severe spasticity

Gastric Stimulation Systems

Medtronic Enterra2 Hero

The Medtronic Enterra Therapy* system uses an implanted neurostimulator to generate mild electrical pulses that are sent through insulated wires (leads) to the lower stomach. This may help control chronic, drug-refractory (resistant to medication) nausea and vomiting due to gastroparesis caused by diabetes or an unknown origin.


Nausea and vomiting associated with gastroparesis

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* The Medtronic Therapy for this disorder is available through a Humanitarian Device Exemption in the United States. The effectiveness of the therapy for this disorder has not been demonstrated.

Sacral Neuromodulation Systems

Sacral Neuromodulation System located near tailbone

Medtronic Sacral Neuromodulation, delivered by the InterStim® System, offers long-term control of bladder control and bowel control symptoms through modulation of the nerves that help control the pelvic floor and lower urinary tract.

The implantable neurostimulation system uses a neurostimulator and lead to send mild electrical pulses to an area near the sacral nerve to the brain. The stimulation parameters are controlled by external, handheld clinician and patient programmers.


Bladder: Overactive bladder, urinary retention not caused by an obstruction
Bowel: Chronic bowel incontinence

Spinal Cord Stimulation Systems

Spinal Cord Stimulation device for chronic pain management

Spinal cord stimulation (also known as neurostimulation therapy) is delivered with a neurostimulator and lead(s) implanted under the skin and adjusted with a clinician and a patient programmer. The system sends mild electrical impulses to an area near the spine, which disrupts pain signals traveling between the spinal cord and brain so patients may feel pain relief.

Patients can adjust the strength and location of stimulation using a handheld programmer. For example, patients can regulate different levels of stimulation at different times of the day or for various activities – such as walking, sleeping, or sitting. Depending on the neurostimulation system, the device may feature adaptive stimulation that automatically adjusts stimulation strength based on the patient's needs and preferences in different positions.

Patients may be able to get a spinal cord stimulator with SureScan® MRI technology that allows them to have a safe access to MRI scans on any part of their body.**


Chronic pain

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**Icon AlertUnder specific conditions; requires SureScan® implantable neurostimulator and Vectris® SureScan leads. Refer to approved labeling for complete list of conditions.

Last updated: 2 Oct 2014

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Additional information

At a Glance

FY2014 Revenue


Neuromodulation accounted for $1.9 billion, or 11%, of our $17 billion in total FY2014 revenue.

Tom Tefft

Thomas Tefft

Minneapolis, Minnesota