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Oxygenation Systems Physician Information > Cardiovascular Surgery > Arrested Heart Surgery
> Adult Perfusion Circuit > Oxygenation Systems
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Silicone Rubber Imitates the Natural Gas Exchange Process in the Human Lung

Medtronic’s ECMO Oxygenators and Surgical Membrane Oxygenators feature a silicone membrane with unique gas transfer properties. Around the world, clinicians choose silicone membrane oxygenators for life-saving procedures.

Typical hollow fiber membrane

Most hollow fiber membrane oxygenators consist of microporous material. Gas exchange takes place by bulk gas transfer via a direct gas to blood interface.


Typical hollow fiber design with a direct gas to blood interface through an open pore.

 

Medtronic silicone membrane

Medtronic solid silicone membrane oxygenators consist of a flat, reinforced silicone membrane envelope that is wound in a spiral coil around a polycarbonate spool. The silicone membrane acts as a highly gas-permeable barrier separating blood and gas compartments. There is no direct blood/gas interface. Gas transfer occurs by molecular diffusion as it does in the human lung. The unique properties of the non-microporous silicone membrane include:

  • Physiologically inert
  • Thromboresistant
  • Non-toxic/Biocompatible
  • Electrochemically identical to the normal capillary
  • Effective gas transfer characteristics

Medtronic silicone membrane
Gas exchange by diffusion through a semi-permeable membrane.

 

Medtronic

Surgical Extracorporeal Perfusion Products

Silicone Membrane Solutions for Extracorporeal Circulation

Silicone Membrane Solutions for Extracorporeal Circulation

I-Series Oxygenators

I-Series Surgical Membrane Oxygenators are used in an extracorporeal perfusion circuit to oxygenate and remove carbon dioxide from the blood during routine cardiopulmonary bypass procedures.

  • Biocompatible silicone polymer membrane
  • Gas transfer by molecular diffusion provides efficiency and safety
  • Integral stainless steel heat exchanger cools and warms the blood
  • Counter current gas and blood flow
  • Three models: I-2500, I-3500, I-4500

I-Series Oxygenator Specifications
Model I-2500 I-3500 I-4500
Surface Area 2.5 m2 3.5 m2 4.5 m2
Static Priming Volume 455 mL 575 mL 665 mL
Maximum Gas Flow Rate 7.5 L/min 10.5 L/min 13.5 L/min
Maximum Blood Flow Rate 4.5 L/min 5.5 L/min 6.5 L/min
Recommended Maximum Sizing by Patient Weight 70 kg 95 kg 96 kg
Blood Port Dimensions 3/8 in 3/8 in 3/8 in
Compliance* 32 mL/100mmHg 45 mL/100 mmHg 59 mL/100 mmHg
Maximum Blood Phase Pressure Drop 300 mmHg 300 mmHg

300 mmHg

Maximum Blood Outflow Pressure 400 mmHg 400 mmHg 400 mmHg
Maximum Transmembrane Pressure 750 mmHg 750 mmHg 750 mmHg

* Blood compartment volume increase (mL) per 100 mmHg applied transmembrane pressure. Transmembrane pressure (TMP) = the pressure in the blood compartment minus the pressure in the gas compartment.


Dual Oxygenator HolderOxygenator HolderI-Series Oxygenator Holders

  • Ensures secure placement of the oxygenator
  • Provides flexibility for custom applications
  • One holder fits all three oxygenator models
  • Single and dual holders available


BIOtherm™ Heat Exchanger

The BIOtherm Heat Exchanger is used during cardiopulmonary support procedures to cool and warm the blood. Typical applications include total body perfusion, coronary perfusion, rapid infusion, and cardioplegia.

  • Stainless steel heat exchanger tubes providing reliable and consistent performance
  • Double seal between blood and water compartments for added safety
  • Silicone coating applied to stainless steel tubes and inserts to enhance blood biocompatibility
  • Blood flow rate up to 6 L/min

Heat Exchanger Specifications  
Model BIOtherm
Priming Volume 135 mL
Water Phase Pressure Limit 45 psi
Maximum Blood Flow Rate 6 L/min
Blood Port Dimensions 3/8 in
Water Port Dimensions 1/2 in

 

BioTherm Performance

BioTherm Performance Factor

BioTherm Blood Flow Rate

Medtronic® Custom Tubing Packs

Custom tubing packs from Medtronic provide top quality products packaged to meet individual needs.

  • Lightweight, easy-to-handle packaging
  • Pre-connected components for time savings and ease of circuit set-up
  • Contribute to cost efficiencies by reducing inventory and material handling
  • Responsive customer service and support
 
> Download the Silicone Membrane Brochure

 

 

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