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T2T™ Heparin Biocompatible Surfaces
Because blood is naturally compatible with vascular endothelium, not artificial circuits
Pioneering.
- Medtronic has more than a decade of expertise and worldwide leadership in heparin biocompatible surface technology for cardiopulmonary bypass.
Committed.
- Tip to tip, we are committed to providing fully coated circuits with heparin biosurfaces.
Flexible.
- Our Carmeda* and Trillium® ;** product offering allows flexible tailoring of coated circuits to meet the unique requirements of patients and cardiovascular surgery teams.
Scientifically Sound.
- Medtronic is dedicated to providing the clinically and scientifically demonstrated benefits of heparin biocompatible surface technology.
Medtronic T2T™ Heparin Biocompatible Surfaces
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Carmeda® |
Trillium® |
| Heparin |
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| • Covalent bond |
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| • End Point Attached |
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| • Non-leaching |
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| • Measured bioactivity |
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| Negative charge |
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| • Heparin |
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| • Sulphate/sulfonate groups |
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| Hydrophilicity |
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| • Hydrophilic primer |
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| • Polyethylene oxide chains (PEO) |
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| Complete coverage |
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| Trillium® and Carmeda® heparin biocompatible surfaces mimic critical characteristics of vascular endothelium for thromboresistance and biocompatibility. |
- Healthy vascular endothelium is the ultimate biocompatible surface.
- Heparin biosurfaces mimic critical properties of the vascular endothelium for thromboresistance and biocompatibility.
- Clinical and scientific research demonstrates the multiple impact of heparin biosurfaces on thromboresistance and biocompatibility.
- Heparin biosurfaces are the best-researched biosurface technology for cardiopulmonary bypass, with more than 500 studies published to date.
Impact of Heparin Biosurfaces
Research indicates that heparin biosurfaces have mitigating effects across several body defensive systems and at multiple points in the coagulation cascade.
With the addition of Trillium® ** Biosurface to Medtronics Gold Standard Carmeda®* BioActive Surface, the ease of providing your patients with the demonstrated benefits of heparin biosurfaces has never been greater.
Ask your Medtronic Representative today how T2T™ can benefit your patients.
* Manufactured under license from Carmeda AB, Sweden. Carmeda is a registered trademark of Carmeda AB.
** Technology licensed under agreement from BioInteractions, Limited, United Kingdom.
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