Mosaic^® and Mosaic Ultra^® Bioprostheses

Exclusive Third Generation Technology Featuring Cinch® Implant System

Implantability Learn more >>

• Access Tight Sinotubular Space
• Flexible Stent to Reduce Tissue Stress
• Especially Suited for Minimally Invasive Procedures

Durability

• AOA^® Tissue Treatment helps mitigate valve calcification¹ Learn more >>
• Physiologic Fixation™ Process preserves leaflet structure and provides leaflets that function similarly to native aortic valves^2,3 Learn more >>

Hemodynamics

• Leaflets open physiologically for excellent forward flow⁴
• Designed by nature to minimize backflow and prevent regurgitation

The Mosaic Ultra^® has a reduced sewing cuff that allows greater flexibility to implant a larger valve size for improved hemodynamics. Its scalloped sewing ring conforms to the aortic annulus for complete supra-annular placement.

PDFs to View & Download

• Product Brochure
• In-Service Guide
• Specifications and Ordering Information

References:

1. Bakhtiary F, et al. Opening and closing kinematics of fresh and calcified aortic vlave prostheses: an in vitro study. J Thorac Cardiovasc Surg 2007;134:657-62.
2. Chen W, et al. Mechanism of efficacy of 2-Amino Oleic Acid for inhibition of calcification of glutaraldehyde-pretreated porcine bioprosthetic heart valves. Circulation 1994;90:323-9.
3. Girardot MN, et al. Role of glutaraldehyde in calcification of procine heart valves: comparing cusp and wall. J Biomed Mater Res 1995;29(7):793-801.
4. Bakhtiary F, et al. Opening and closing kinematics of fresh and calcified aortic valve prostheses: an in vitro study. J Thorac Cardiovasc Surg 2007;134:657-62.

No clinical data are available which evaluate the long-term impact of AOA^® tissue treatment and the Physiologic Fixation process in patients.

Mosaic, Mosaic Ultra and Cinch are registered trademarks of Medtronic, Inc. Physiologic Fixation is a trademark of Medtronic, Inc. AOA is a registered trademark of Biomedical Design, Inc., Atlanta, Georgia.