Overview:

BIS™ Monitoring to Help Improve Anesthesia-Related Outcomes

With the BISx™ OEM module from Medtronic, BIS™ brain monitoring technology can be easily integrated into medical devices in a wide range of healthcare settings—from acute care monitors in operating rooms and intensive care units to preconfigured devices in ambulatory surgery centers or procedural sedation locations.
 

When you integrate the BISx™ OEM module into your anesthesia and sedation monitoring systems, you can offer your customers the industry’s most widely studied and published level of consciousness monitoring parameter. BIS™ technology can provide insight into the direct and patient-specific effects of anesthesia on the brain to enhance perioperative outcomes.

Technology:

BIS™ Brain Monitoring Technology Advantages

Based on the scientifically validated BIS™ algorithm, BIS™ brain monitoring technology uses innovative technology to link patient-specific EEG information to the individual clinical state of each patient.


Clinical Benefits of BIS™ Brain Monitoring Technology

Anesthesia-related clinical benefits include

  • Up to 23% decrease in anesthetic drug use([FOOTNOTE=Gan TJ, Glass PS, Windsor A, et al. Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil, and nitrous oxide anesthesia. BIS™ Utility Study Group. Anesthesiology. 1997;87:808-815.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35754])
  • Up to 40% faster wake-up time([FOOTNOTE=Gan TJ, Glass PS, Windsor A, et al. Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil, and nitrous oxide anesthesia. BIS™ Utility Study Group. Anesthesiology. 1997;87:808-815.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35754])
  • Faster recovery and extubation times([FOOTNOTE=PunjasawadwongY, Boonjeungmonkol N, Phongchiewboon A. Bispectral index for improving anaesthetic delivery and postoperative recovery. Cochrane Database of Systematic Reviews. 2007;17(4):CD003843.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=185841])
  • 87% increase in “excellent/fully oriented” status on PACU admission([FOOTNOTE=Gan TJ, Glass PS, Windsor A, et al. Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil, and nitrous oxide anesthesia. BIS™ Utility Study Group. Anesthesiology. 1997;87:808-815.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35754])
  • 32% faster eligibility for PACU discharge([FOOTNOTE=White PF, Ma H, Tang J, et al. Does the use of electroencephalographic bispectral index or auditory evoked potential index monitoring facilitate recovery after desflurane anesthesia in the ambulatory setting? Anesthesiology. 2004;100:811-817.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35731])
  • 80% lower incidence of intraoperative([FOOTNOTE=Myles PS, Leslie K, McNeil J, et al. Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomized controlled trial. Lancet. 2004;363:1757-1763.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35729]),([FOOTNOTE=Avidan MS, et al. Anesthesia awareness and the bispectral index. N Engl J Med. 2008;13;358(11):1097-1108. ],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=185918]),([FOOTNOTE=Avidan MS, et al. Prevention of intraoperative awareness in a high-risk surgical population. N Engl J Med. 2011;18;365(7):591-600.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=301466]),([FOOTNOTE=Ekman A, Lindholm ML, Lennmarken C, et al. Reduction in the incidence of awareness using BIS™ monitoring. Acta Anaesthesiol Scand. 2004;48:20-26. ],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=117525]) awareness with recall in adults
  • Improved patient satisfaction([FOOTNOTE=Luginbuhl M, Wuthrich S, Petersen-Felix S, et al. Different benefits of bispectral index (BIS™) in desflurane and propofol anesthesia. Acta Anaesthesiol Scand. 2003;47:165-173.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35736])


How Advanced BIS™ Technology Works

  • Raw EEG data are obtained through one of several specially designed BIS™ sensors placed on the patient’s forehead.
  • The BIS™ sensor non-invasively collects the raw EEG data that indicates the multifaceted electrical activity of the brain in real time.
  • The scientifically validated BIS™ algorithm then filters, analyzes and correlates this data, quantifying only the change in the bispectrum and other EEG features that apply to the individual’s current clinical state.
  • The results are continually consolidated and displayed as the clinically validated BIS™ index, a number between 0 and 100 that indicate the patient’s response to anesthetic agents.