Continuous Monitoring for Cryptogenic Stroke

Detecting AF with Long-Term Monitoring

There are a variety of monitoring methods used to detect atrial fibrillation in practice today:

Intermittent and Symptom-based Monitoring:

  • EKG
  • Holter monitor
  • External loop recorder
     

Long-term Monitoring:

  • Insertable cardiac monitor

You may be surprised to learn that intermittent and symptom-based monitoring is highly inaccurate for identifying patients with any or long-duration atrial tachycardia/atrial fibrillation (AT/AF) and for assessing AT/AF burden.1 In fact, the more complex and longer the method of (external) monitoring that is used, the lower the patient compliance.2 How can you improve AF detection? Studies show that in cryptogenic stroke patients, longer monitoring increases AF detection. In the studies highlighted in the chart below, notice the percentage of patients with detected AF compared to monitoring duration:


Author Monitor Type % Patients with
Dectected AF
Definition of AF
Jabaudon3 24-hour Holter 5% No defined duration
Bansil4 48-hour Holter 5% No defined duration
Jabaudon3 7-day Holter 5.7% No defined duration
Tayal5 21-day Monitor 23% 85% of episodes less than or equal to 30 seconds of duration
Zeigler6 1.2-years Continuous Monitoring 28% 5 min. duration

In one recent study, the majority of newly detected AF patients (73%) had AT/AF on <10% of follow-up days, making it highly unlikely to be detected by standard monitoring techniques.6
 

 

References
1. Ziegler P. Comparison of continuous versus intermittent monitoring of atrial arrhythmias. Heart Rhythm 2006;3:1445–1452.
2. Calkins, et al. Heart Rhythm. Jun 2007;4(6):816-61.
3. Jabaudon D, Sztajzel J, Sievert K, Landis T, Sztajzel R. Usefulness of ambulatory 7-day ECG monitoring for the detection of atrial fibrillation and flutter after acute stroke and transient ischemic attack. Stroke. July 2004; 35(7): 1647-1651. Originally published online May 20, 2004.
4. Bansil S, Karim H. Detection of atrial fibrillation in patients with acute stroke. J Stroke Cerebrovasc Dis. 2004;13:12-15.
5. Tayal,et al. Neurology 2008;71:1-1.
6. Ziegler P. et al. Stroke. 2010;41.

 

Last updated: 26 Feb 2013

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