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What Is Infuse Bone Graft and the LT-Cage Device?

Infuse® Bone Graft and the LT-Cage® Device are used in a surgery called an Anterior Lumbar Interbody Fusion (ALIF). Using Infuse Bone Graft inside an LT-Cage Device can reduce the pain and complications associated with treating degenerative disc disease (DDD) by eliminating a second surgery to harvest bone from a patient's own hip for transplantation to the spine, as is done in traditional spinal fusion procedures.

Infuse Bone Graft and the LT-Cage Device are designed to aid in the treatment of degenerative disc disease. The product consists of a small, hollow metal cylinder (the LT-Cage Device) and a bone graft substitute (Infuse Bone Graft).

The LT-Cage Device is intended to restore the degenerated disc space to its original height, thereby relieving the pressure on your nerves. Two implants are placed side by side. The Infuse Bone Graft component is used to fill the small, thimble-like LT-Cage Devices. The cages stabilize the spine while fusion occurs and maintain the proper height between the vertebrae.

The Infuse Bone Graft consists of two parts – a solution containing rhBMP-2 (recombinant human Bone Morphogenetic Protein-2) and an absorbable collagen sponge. The protein is a manufactured (genetically engineered) version of a natural protein normally found in small quantities in the body.

The purpose of the protein is to stimulate bone formation. During surgery, the protein solution is soaked into the sponge. The sponge acts as a scaffold for the formation of new bone that the protein stimulates. The sponge is manufactured from bovine (cow) Type I collagen. It is designed to resorb (disappear) over time.

Information on this site should not be used as a substitute for talking with your doctor. Always talk with your doctor about diagnosis and treatment information.

Last updated: 22 Sep 2010

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