Advantages of Activa Therapy
Reversible
Unlike lesion procedures such as pallidotomy and thalamotomy, Activa Therapy is reversible in that the system components may be completely removed, preserving options for future therapies. 1,2-6
Adjustable
Using a non-invasive clinical programmer, neurologists can fine-tune stimulation parameters to maximize therapeutic benefit and minimize side effects.2,3,4,5,6,7
References
- Data on file at Medtronic.
- Starr PA, Vitek JL, Bakay RAE. Ablative surgery and deep brain stimulation for Parkinson's disease. Neurosurgery. 1998;43:989-1015.
- Ardouin C, Pillon B, Peiffer E, et al. Bilateral subthalamic or pallidal stimulation for Parkinson's disease affects neither memory nor executive functions; a consecutive series of 62 patients. Ann Neurol. 1999;46:217-223.
- French study: Haberler C, Alesch F, Mazal PR, et al. No tissue damage by chronic deep brain stimulation in Parkinson's disease. Ann Neurol. 2000;48:372-376.
- Olanow CW, Brin MF, Obeso JA. The role of deep brain stimulation as a surgical treatment for Parkinson's disease. Neurology. 2000;55(Suppl 6):S60-S66.
- Benabid AL, Benazzouz A, Hoffmann D, et al. Long-term electrical inhibition of deep brain target in movement disorders. Mov Disord. 1998;13(Suppl 3):119-125.
- The Deep-Brain Stimulation for Parkinson's Disease Study Group. Deep-brain stimulation of the subthalamic nucleus or the pars interna of the globus pallidus in Parkinson's disease. N Engl J Med. 2001;345:956-63.
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