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Activa® Therapy

Activa Tremor Control Therapy Bibliography

Note that the articles listed in these bibliographies may include information about an Activa System device or a use of brain stimulation that has not been approved by the U.S. Food and Drug Administration.

General Information

Hubble J, et al. Deep Brain Stimulation for Essential Tremor. Neurology 1996: 46, 1150-1153.

Koller W, et al. Deep Brain Stimulation of the VIM Nucleus of the Thalamus for the Treatment of Tremor. Neurology 2000: 55 (Supp 6) S29-33.

Lozano A. Vim Thalamic Stimulation for Tremor. Arch Med Res 2000: 31, 266-269.

Starr P, et al. Deep Brain Stimulation for Movement Disorders. Neurosurgery Clinics of North America. 1998: 9(2): 381-402.

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Safety and Efficacy

Bryant J, et al, The Impact of Thalamic Stimulation of Activities of Daily Living for Essential Tremor. Surg Neurol 2003: 59, 479-485.

Koller W, et al. High-Frequency Unilateral Thalamic Stimulation in the Treatment of Essential and Parkinsonian Tremor. Ann Neuro 1997: 42(3), 292-298.

Krauss J. Concepts and Methods in Chronic Thalamic Stimulation for Treatment of Tremor: Technique and Application. Neurosurgery 2001;48:535-543.

Schuurman PR, Bosch DA, Bossuyt PM, Bonsel GJ, van Someren EJ, de Bie RM, Merkus MP, Speelman JD. A comparison of continuous thalamic stimulation and thalamotomy for suppression of severe tremor. N Engl J Med. 2000 Feb 17;342(7):461-468.

Tasker R. Deep Brain Stimulation is Preferable to Thalamotomy for Tremor Suppression. Surg Neurol 1998:49, 145-154.

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Long-term Outcomes

Benabid AL, et al. Long Term Electrical Inhibition of Deep Brain Targets in Movement Disorders. Mov Disorders 1998: 13 (Supp 3), 119-125.

Koller W, et al. Long-Term Safety and Efficacy of Unilateral Deep Brain Stimulation of the Thalamus in Essential Tremor. Mov Disord. 2001: 16, 464-468.

Lyons K, et al. Long Term Safety and Efficacy of Unilateral Deep Brain Stimulation of the thalamus for Parkinsonian Tremor. J Neurol Neurosurg Psychiatry 2001: 71, 682-684.

Rhencrona S, et al. Long-Term Efficacy of Thalamic Deep Brain Stimulation for Tremor: Double-Blind Assessments. Mov Disord 2003:18, 163-170.

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Quality of Life and Neuropsychological Outcomes

Fields J, et al. Neuropsychological and Quality of Life Outcomes 12 Months after Unilateral Thalamic Stimulation for Essential Tremor. J Neurol Neurosurg Psychiatry 2003: 74, 305-311.

Hariz G, et al. Impact of Thalamic Deep Brain Stimulation on Disability and Health-Related Quality of Life with Essential Tremor. J Neurol Neurosurg Psychiatry 2002: 72, 47-52.

Troster A, et al. Neuropsychological and Quality of Life Outcome after Thalamic Stimulation for Essential Tremor. Neurology 1999:53, 1774-1780.

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Patient Selection

Deuschl G, et al. Deep Brain Stimulation for Trauma [sic]: Patient Selection and Evaluation. Mov Disord 17(Supp 3), S102-111.

Pillon B. Neuropsychological assessment for management of patients with deep brain stimulation. Mov Disord. 2002: 17(Supp 3), S116-122.

Saint-Cyr J, et al. Neuropsychological assessment of patients for movement disorder surgery. Mov Disord. 2000: 15, 771-783.

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Patient Management

Dowsey-Limousin P. Postoperative Management of Vim DBS for Tremor. Mov Disord 17 (Supp 3), S208-211.

Volkman J, et al. Introduction to the Programming of Deep Brain Stimulators. Mov Disord 2002: 17(Supp 3), S181-187.

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Surgical Information

Benabid AL, et al. Imaging of Subthalamic Nucleus and Ventralis Imtermedius of the Thalamus. Mov Disord 2002: 17(Supp 3) S123-129.

Garonzik I, et al. Intraoperative Microelectrode and Semi-Microelectrode Recording During the Physiological Localization of the Thalamic Nucleus Ventral Intermediate. Mov Disord 2002: 17(Supp 3) S135-144.

Speelman J. Stereotactic Neurosurgery for Tremor. Mov Disord 2002: 17(Supp 3) S84-88.

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Additional Information

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