Marquis^® Family of ICDs

Convenience, Performance and Safety

Marquis DR
Model 7274

Convenience

• Leadless™ ECG enables you to approximate a surface ECG, and record cardiac activity and perform tests without attaching separate ECG leads
• RapidRead™ telemetry offers up to a 20x improvement in telemetry speed ¹
• Automatic daily P- and R-wave amplitudes and pacing/painless HV lead impedance measurements. Measurements trended for over 80 weeks for long term lead impedance measurement ²
• One page Cardiac Compass^® report graphically displays your patient’s clinical progress for up to 14 months
• Leading Internet-based technology for remote patient follow-up, the Medtronic CareLink^® Network , empowers you to improve clinic operations and enhance patient care.

Performance:

Marquis VR
Model 7230

• Battery technology delivers short, consistent charge times to full output (30J delivered)
  • Ensure the greatest safety margin with the shortest time to therapy
  • 5.9 seconds at BOL to 7.5 seconds (7.7 seconds for VR) at ERI^a
• A reduction of the charging time may help to prevent pre-shock syncopies ^3,4
• Cost-effective therapy:
  • Marquis DR longevity of 8 years at 50% pacing with biannual charges ⁵
  • Marquis VR longevity of 10 years at 50% pacing with biannual charg

Safety:

Identify system issues before they become clinical problems

• Expanded Patient Alert™ – exclusive to Medtronic – provides 6 new indicators to alert the patient when follow-up care is needed
  • More than 90% of alert tones identify clinically significant patient safety issues that require physician intervention⁶
• Fewer inappropriate therapies: Enhanced PR Logic™  dual chamber detection delivers up to 95.2% accuracy (Positive Predictive Value, or PPV) in delivered therapies⁷
• High-resolution detection: New Wavelet™ Dynamic Discrimination criterion - exclusive to Marquis VR - compares the morphology of the arrhythmia to a sinus rhythm template for more accurate classification
  • Template of QRS complex is updated by the Auto Template feature when sinus rhythm changes
  • Easy to program

Medtronic CareLink® Network

• The industry’s first Internet-based remote monitoring service that is comparable to an in-office device check
• Connects Marquis patients who are at home or traveling with physicians for “virtual office visits”
• Physicians can access device data anytime, from any Web-capable PC
• Provides comprehensive device data in approximately one-third the time of a typical office visit

References

1. Compared to Medtronic GEM^® III DR Model 7275 ICD.
2. DR has P- and R-wave. Marquis VR has only R-wave.
3. Himmrich E, Przibille O, Liebrich D, Zellerhoff C, Rosocha S. Pre-shock syncopy in patients with implanted defibrillators - incidence and reasons. Cardiostim Abstract #1180 (122/5), 2000.
4. Gradaus R, Bode-Schnurbus L, Weber M, et al. Effect of ventricular fibrillation duration on the defibrillation threshold in humans, PACE. 2002;25:14-19.
5. Pacing parameters: 60 ppm, 2.5 V, 0.4 ms, 900; charges are 30J maximum energy shocks or capacitor reformations.
6. Iowa Heart Center (Des Moines, Iowa, USA) single-center study of 215 GEM^®Family ICDs with Patient Alert™ programmed ON. Data on file.
7. Wilkoff BL, Gillberg JM, DeSouza CM. The Enhanced PR Logic dual chamber tachyarrhythmia detection algorithm: retrospective analysis of supraventricular tachycardia with long PR intervals. JACC Abstract #873-4, Feb. 2001.

Notes
^aA charge is a maximum-energy shock or capacitor reformation.

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