CIDS TRIAL: ICD vs. Antiarrhythmic Drug Treatment for VF or Sustained VT¹

CIDS- Canadian Implantable Defibrillator Study

Protocol:

Hypothesis:

Initial ICD therapy will reduce the risk of arrhythmic death compared to amiodarone for patients at high risk for arrhythmic death due to VT/VF.

Primary endpoint:

Total mortality

Status:

Start: 1990
Completion: 1998

Results:

The ICD group experienced a 20% relative reduction in mortality in three years (P=0.14).

Reference

1. Connolly S, Gent M, Roberts R, for the CIDS investigators. Canadian Implantable Defibrillator Study (CIDS). A randomized trial of the implantable cardioverter defibrillator against amiodarone. Circulation. 2000,101:1297-1302.

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