Healthcare Professionals

Bioresorbable Ear Packing and Patching Products

for Middle Ear Surgery and Other Otologic Procedures

EpiFilm and EpiDisc Otologic Laminae

EpiFilm and EpiDisc Otologic Laminae are bioresorbable film scaffolds with thousands of microperforations that help the body repair and regrow tissue after middle ear surgery.

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EpiFilm and EpiDisc Otologic Laminae

EpiFilm and EpiDisc Otologic Laminae

Cell Migration into EpiFilm/EpiDisc Microperforations

SEM: Keratinocytes migrating into microperforations

EpiFilm® and EpiDisc® Otologic Laminae are bioresorbable, implantable ear packing and patching devices composed of esterified hyaluronic acid (HYAFF®).

EpiFilm Otologic Lamina

After a tympanoplasty, EpiFilm Otologic Lamina has been shown to aid the healing of the mastoid cavity. The 2.5 cm x 2.5 cm matrix is useful for myringoplastic and tympanoplastic procedures, such as:

  • Covering exposed ear canal walls
  • Reconstruction of the tympanic membrane when used with fascia or other tissue graft techniques
  • Lining the mastoid cavity

EpiDisc Otologic Lamina

EpiDisc Otologic Lamina is a pre-cut 8.0 mm disc of EpiFilm lamina, packaged 2 per box. This makes it ideal for use during tympanoplasties or repairing tympanic membrane perforations.

Hyaluronic Acid and Middle Ear Surgery

In middle ear surgery, biocompatible1-7 hyaluronic acid has been shown to improve the natural healing of the mastoid cavity following tympanoplasty and help reduce fibrous scarring.1-4

Additional Ear Packing and Patching Products

See the ENT Product Catalog for all ear packing products, including traditional ear packing and wicks.

HYAFF® is a registered trademark of Anika Therapeutics SRL.

 


References

1

Sayin I, Kaya KH, Ekizoğlu O, Erdim I. A prospective controlled trial comparing spontaneous closure and EpiFilm patching in traumatic tympanic membrane perforations. Eur Arch Otorhinolaryngol. 2012. Epub: 2013 January 5. doi: 10.1007/s00405-012-2331-x.

2

Saliba I, Knapik M, Froehlich P, Abela A. Advantages of hyaluronic acid fat graft myringoplasty over fat graft myringoplasty. Arch Otolaryngol Head Neck Surg. 2012; 138(10):950-955.

3

Martini A, Morra B. Use of a hyaluronan-based biomembrane in the treatment of chronic cholesteatomatous otitis media. Am J Otology. 2000; 21:468-473.

4

Laurent C, Hellstrom S, Stenfors L. Hyaluronic acid reduces connective tissue formation in middle ears filled with absorbable gelatin sponge: an experimental study. Am J Otolaryngol. 1986; 7:181-186.

5

Pirnazar P, et al. Bacteriostatic effects of hyaluronic acid. J Periodontol. 1999; 70:370-374.

6

Longaker MT, et al. Studies in fetal wound healing. A prolonged presence of hyaluronic acid characterized wound fluid. Annals of Surgery. 1991; 213:292-296.

7

Grainger DA, et al. The use of hyaluronic acid polymers to reduce postoperative adhesions. J Gynecol Surg. 1991; 7:97-101.

How they Work