Clinical Outcomes Cardiac Ablation for Atrial Fibrillation
Arctic Front Advance™ Cryoballoon has demonstrated consistent outcomes among various centers.
Arrhythmia monitoring methods and definition of procedure success
(Freedom from AF Only or AF/AT/AFL) varied between studies.
Among centers with varying annual ablation volume, Arctic Front Advance Cryoballoon resulted in more consistent outcomes compared to radiofrequency.
* Standard deviations were smaller in the cryoballoon group for all three procedure time measures, indicating more consistent times with less variation from the mean.
** Protocol required 30 min. waiting period after last application to assess PV isolation.
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Kumar, et al. Adenosine testing after second-generation balloon devices (cryothermal and laser) mediated pulmonary vein ablation for atrial fibrillation. J Interv Card Electrophysiol. 2014; 41(1):91-97.
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Tebbenjohanns, et al. Shortening of freezing cycles provides equal outcome to standard ablation procedure using second-generation 28 mm cryoballoon after 15-month follow-up. Europace. 2016; 18(2):206-10.
Wissner, et al. One-year clinical success of a 'no-bonus' freeze protocol using the second-generation 28 mm cryoballoon for pulmonary vein isolation. Europace. 2015; 17(8):1236-40.
Providencia, et al. Cryoballoon or radiofrequency ablation for atrial fibrillation. New England Journal of Medicine. 2016; 375(11):1099.
Kuck, et al. Cryoballoon or Radiofrequency Ablation for Paroxysmal Atrial Fibrillation. N Engl J Med. 2016; 374(23): 2235-45.