Atrial fibrillation detection and treatment matters
Cryptogenic stroke accounts for approximately one-third of ischemic strokes in the modern stroke registries and databases.2
Cryptogenic stroke is as prevalent as large vessel stroke.
The CRYSTAL-AF Study found that short- and intermediate-term cardiac monitoring may miss many patients with paroxysmal AF.
* See full brief statement for complete indications for use.
** ABCD2 Score >5
American Heart Association. Heart Disease and Stroke Statistics, 2015 Update. Available at: http://www.heart.org/HEARTORG/General/Heart-and-Stroke-Association-Statistics_UCM_319064_SubHomePage.jsp. Accessed April 12, 2015.
Sacco RL, Ellenberg JH, Mohr JP, et al. Infarcts of undetermined cause: the NINCDS Stroke Data Bank. Ann Neurol. April 1989;25(4):382-390.
Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation: a major contributor to stroke in the elderly. The Framingham Study. Arch Intern Med. September 1987;147(9):1561-1564.
Lin HJ, Kelly-Hayes M, Beiser AS, et al. Stroke Severity in Atrial Fibrillation: The Framingham Study. Stroke. 1996; 27: 1760-1764.
Stroke Prevention in Atrial Fibrillation Study. Final results. Circulation. August 1991;84(2):527-539.
WJ, et al. Stroke 2018; doi: 10.1161/STR.0000000000000158. [Epub ahead of print]
Kirchhof P, Benussi, S, Kotecha D, et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Eur Heart J. Published online August 27, 2016. Accessed online August 31, 2016 at: http://eurheartj.oxfordjournals.org/content/early/2016/08/26/eurheartj.ehw210.
Sanna T, Diener HC, Passman RS, et al. Cryptogenic stroke and underlying atrial fibrillation. N Engl J Med. June 26, 2014;370(26):2478-2486.
Hart RG, Diener HC, Coutts SB, et al. Embolic strokes of undetermined source: the case for a new clinical construct. Lancet Neurol. April 2014;13(4):429-438.