CLINICAL EVIDENCE ACUTE ISCHEMIC STROKE THERAPIES

SOLITAIRE STENT RETRIEVER 

Studies prove the Solitaire device reduces stroke-related disability in patients suffering large vessel acute ischemic stroke (AIS) following IV t‑PA.1–5

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SWIFT PRIME STUDY

A key study measuring the effectiveness of the Solitaire device following IV t‑PA for patients experiencing an AIS due to large vessel occlusion.

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STANDARD OF CARE

The 2015 AHA/ASA guidelines6 recommend the use of endovascular treatment with stent retrievers, like the Solitaire device, following IV t‑PA for eligible patients experiencing AIS.

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1

SWIFT PRIME- Saver JL, Goyal M, Bonafe A, et al. Stent-retriever thrombectomy after intravenous t‑PA vs. t‑PA alone in stroke. N. Engl. J. Med. Jun 11 2015; 372(24):2285-2295.

2EXTEND-IA- Campbell BC, Mitchell PJ, Kleinig TJ, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N. Engl. J. Med. Mar 12 2015; 372(11):1009-1018.

3ESCAPE- Goyal M, Demchuk AM, Menon BK, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N. Engl. J. Med. Mar 12 2015; 372(11):1019-1030.

4REVASCAT- Jovin TG, Chamorro A, Cobo E, et al. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N. Engl. J. Med. Jun 11 2015; 372(24):2296-2306.

5MR CLEAN- Berkhemer OA, Fransen PS, Beumer D, et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N. Engl. J. Med. Jan 1 2015; 372(1):11-20.

6Powers WJ, Derdeyn CP, Biller J, et al. 2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients with Acute Ischemic Stroke Regarding Endovascular Treatment: A Guideline for Healthcare Professionals from the American Heart Association/American Stroke Association. Stroke. Oct 2015;46(10):3020-3035.