CLINICAL EVIDENCE—FLOW DIVERSION BRAIN ANEURYSM THERAPIES
PUFs (Pipeline™ Embolization Device for Uncoilable or Failed Aneurysms) was a multicenter, prospective, interventional, single-arm trial to evaluate the safety and effectiveness of the Pipeline implant* in the treatment of complex intracranial aneurysms.
PUFs studied 108 patients with a wide-necked, large, or giant intracranial aneurysm in the petrous, cavernous, or paraophthalmic regions of the internal carotid artery.
Treatment of large and giant saccular and fusiform aneurysms in the internal carotid artery (ICA) with the Pipeline™ device is safe and highly effective.
The PUFs study only included the Pipeline embolization device. The Pipeline Flex embolization device contains the same implant as the Pipeline embolization device.
Results may vary. Not all patients receive the same results.
Becske T. et al., Five-Year Results of the Pipeline for Uncoilable or Failed Aneurysms Trial. Neurosurgery (JNS). Published online Jan. 06, 2017.