The use of LigaSure™ radiofrequency device to seal and divide the major vessels in laparoscopic colorectal resections is associated with a very high success rate.

The results of this large single-centre series demonstrate that use of the LigaSure™ is:




Vessel sealing with LigaSure™ radiofrequency device was effective in 100% of cases.1


Highlighted are countries of origin for publications demonstrating the successful use of LigaSure™ technology in clinical settings across all types of colorectal surgery.

  • 1. Grieco et al.Major vessel sealing in laparoscopic surgery for colorectal cancer: a single-center experience with 759 patients.World Journal of Surgical Oncology (2018) 16:101. https://doi.org/10.1186/s12957-018-1402-x.

  • 2. Rieger, N. A. & Lam, F. F. Single-incision laparoscopically assisted colectomy using standardlaparoscopic instrumentation. Surg. Endosc. Other Interv. Tech. 24, 888–890 (2010). (PMID: 19760335)

  • 3. Brunner, W. et al. Single-access laparoscopic sigmoid resections. Surg. Endosc. Other Interv. Tech. 25,S28–S28 (2011).

  • 4. Kim, D. Y. & Boushey, R. P. The Use of Alternative Energy Sources and New Techniques for theTreatment of Hemorrhoidal Disease. Semin. Colon Rectal Surg. 18, 181–186 (2007).

  • 5. Zhang, H. et al. Transanal single-port laparoscopic total mesorectal excision in the treatment of rectalcancer. Tech. Coloproctol. 17, 117–23 (2013). (PMID: 22936590)

  • 6. Arslani, N., Patrlj, L., Rajkovic, Z., Papes, D. & Altarac, S. A randomized clinical trial comparing Ligasureversus stapled hemorrhoidectomy. Surg. Laparosc. Endosc. Percutan. Tech. 22, 58–61 (2012). (PMID:22318061)

  • 7. Talha, A., Bessa, S. & Abdel Wahab, M. Ligasure, Harmonic Scalpel versus conventional diathermy inexcisional haemorrhoidectomy: a randomized controlled trial. ANZ J Surg (2014). doi:10.1111/ans.12838(PMID: 25214362)

  • 8. Kössi, J., Luostarinen, M., Kontula, I. & Laato, M. Laparoscopic sigmoid and rectal resection using anelectrothermal bipolar vessel sealing device. J Laparoendosc Adv Surg Tech A 17, 719–722 (2007). (PMID:18158799)

  • 9. Trilling, B., Riboud, R., Abba, J., Girard, E. & Faucheron, J. L. Energy vessel sealing systems versusmechanical ligature of the inferior mesenteric artery in laparoscopic sigmoidectomy. Int. J. ColorectalDis. 31, 903–908 (2016). (PMID: 26841803)

  • 10. Vestweber, B. et al. Single-incision laparoscopic surgery: Outcomes from 224 colonic resectionsperformed at a single center using SILSTM. Surg. Endosc. Other Interv. Tech. 27, 434–442 (2013). (PMID:22806519)

  • 11. Basdanis, G., Papadopoulos, V. N., Michalopoulos, A., Apostolidis, S. & Harlaftis, N. Randomized clinicaltrial of stapled hemorrhoidectomy vs open with Ligasure for prolapsed piles. Surg. Endosc. Other Interv.Tech. 19, 235–239 (2005). (PMID: 15573239)

  • 12. Fok, K. L., Cheung, M. H. Y., Poon, C. M. & Lee, K. W. LigaSure-assisted versus diathermy day casehaemorroidectomy: A randomized controlled trial. Ambul. Surg. 14, no pagination-no pagination (2008).

  • 13. Khanna, R., Khanna, S., Bhadani, S., Singh, S. & Khanna, A. K. Comparison of Ligasure Hemorrhoidectomywith Conventional Ferguson’s Hemorrhoidectomy. Indian J Surg 72, 294–297 (2010). (PMID: 21938191)

  • 14. Bouini, N. R. et al. Randomised Clinical Trial Comparing Ligasure Hemorrhoidectomy with ConventionalHemorrhoidectomy. J. Maz. Univ. Med. Sci. 22, 67–73 (2012).

  • 15. Baig, M. N., Moftah, M., Deasy, J., Mcnamara, D. A. & Cahill, R. A. Implementation and usefulness ofsingle-access laparoscopic segmental and total colectomy. Color. Dis. 14, 1267–1275 (2012). (PMID:22309248)

  • 16. Swaid, F. et al. Totally laparoscopic versus laparoscopic-assisted left colectomy for cancer: aretrospective review. Surg. Endosc. Other Interv. Tech. 30, 2481–2488 (2016). (PMID: 26335075)

  • 17. Franceschilli, L. et al. Radiofrequency versus conventional diathermy Milligan-Morganhemorrhoidectomy: A prospective, randomized study. Int. J. Colorectal Dis. 26, 1345–1350 (2011).(PMID: 21519801)

  • 18. Tsunoda, A. et al. Randomized controlled trial of bipolar diathermy vs ultrasonic scalpel for closedhemorrhoidectomy. World J Gastrointest Surg 3, 147–152 (2011). (PMID: 22110846)

  • 19. Sakr, M. F. & Moussa, M. M. LigaSure hemorrhoidectomy versus stapled hemorrhoidopexy: Aprospective, randomized clinical trial. Dis. Colon Rectum 53, 1161–1167 (2010). (PMID: 20628280)

  • 20. Peralta, G. et al. Massive gastrointestinal bleeding: A rare case of extrarenal, visceral, rectalfibromuscular displasia. Surg. Endosc. Other Interv. Tech. 28, 323 (2014).

  • 21. Nieuwenhuis, D. H., Draaisma, W. A., Verberne, G. H. M., Van Overbeeke, A. J. & Consten, E. C. J.Transanal endoscopic operation for rectal lesions using two-dimensional visualization and standardendoscopic instruments: A prospective cohort study and comparison with the literature. Surg. Endosc.Other Interv. Tech. 23, 80–86 (2009). (PMID: 18443874)

  • 22. Bakhtiar, N., Moosa, F. A., Jaleel, F., Qureshi, N. A. & Jawaid, M. Comparison of Hemorrhoidectomy byligasure with conventional milligan morgan’s Hemorrhoidectomy. Pakistan J. Med. Sci. 32, 657–661(2016). (PMID: 27375709)

  • 23. Szyca, R., Dratwa, S., Tomaszewski, S. & Leksowski, K. Closed hemorrhoidectomy with LigaSure - Aprospective study. Pol. Przegl. Chir. 78, 1415–1420 (2006).

  • 24. Martian, B. V et al. Wise steps in laparoscopic right hemicolectomy: Standardization of the technique incurent use. Surg. Endosc. Other Interv. Tech. 30, S33–S33 (2016).

  • 25. Tulina, I. A., Tsarkov, P. V & Kravchenko, Ay. Laparoscopic ‘no touch’ intersphincteric rectal resection:Three step technique. Surg. Endosc. Other Interv. Tech. 28, S175–S175 (2014).

  • 26. Zubaidi, A., AlDeghaither, S., Alkhayal, K. & Al-Obeed, O. Single-incision laparoscopic colorectal surgery:A report of 33 cases in Saudi Arabia. Ann. Saudi Med. 36, 282–287 (2016). (PMID: 27478914)

  • 27. Kecmanovic, D. M. et al. Bulk agent Plantago ovata after Milligan-Morgan hemorrhoidectomy withLigasureTM. Phyther. Res. 20, 655–658 (2006). (PMID: 16708408)

  • 28. Tan, K. Y. et al. Randomized clinical trial comparing LigaSure haemorrhoidectomy with open diathermyhaemorrhoidectomy. Tech. Coloproctol. 12, 93–97 (2008). (PMID: 18545884)

  • 29. Yun, J. A. et al. Single-incision laparoscopic right colectomy compared with conventional laparoscopyfor malignancy: Assessment of perioperative and short-term oncologic outcomes. Surg. Endosc. OtherInterv. Tech. 27, 2122–2130 (2013). (PMID: 23319285)

  • 30. Castellví, J. et al. LigasureTM versus diathermy hemorrhoidectomy under spinal anesthesia or pudendalblock with ropivacaine: A randomized prospective clinical study with 1-year follow-up. Int. J. ColorectalDis. 24, 1011–1018 (2009). (PMID: 19396451)

  • 31. Hubner, M. et al. Prospective randomized study of monopolar scissors, bipolar vessel sealer andultrasonic shears in laparoscopic colorectal surgery. Br. J. Surg. 95, 1098–1104 (2008). (PMID: 18690630)

  • 32. Chen, C. W., Lai, C. W., Chang, Y. J. & Hsiao, K. H. Modified LigaSure hemorrhoidectomy for thetreatment of hemorrhoidal crisis. Surg. Today 44, 1056–1062 (2014). (PMID: 23812901)

  • 33. Pattana-arun, J., Sooriprasoet, N., Sahakijrungruang, C., Tantiphlachiva, K. & Rojanasakul, A. Closed vsligasure hemorrhoidectomy: A prospective, randomized clinical trial. J. Med. Assoc. Thail. 89, 453–458(2006). (PMID: 16696389)

  • 34. Teksöz, S. et al. Comparison of a vessel sealing system with a conventional technique inhemorrhoidectomy. Balkan Med. J. 28, 189–192 (2011).

  • 35. Vadamalayan, B. et al. Laparoscopic colectomy for ulcerative colitis with associated auto-immune liverdisease and portal hypertension. J. Pediatr. Gastroenterol. Nutr. 62, 329 (2016).

  • 36. Adamina, M., Champagne, B. J., Hoffman, L., Ermlich, M. B. & Delaney, C. P. Randomized clinical trial comparing the cost and effectiveness of bipolar vessel sealers versus clips and vascular staplers for laparoscopic colorectal resection. Br J Surg 98, 1703–1712 (2011). (PMID: 21997317)

  • 37. Nakajima K, Nezu R, Ito T, Nishida T. Hand-assisted laparoscopic restorativeproctocolectomy for ulcerative colitis: the optimization of instrumentation towardstandardization. Surg Today. 2010;40(9):840-4. doi:10.1007/s00595-009-4157-8.PMID:20740347

  • 38. Takiguchi N, Nagata M, Soda H, Nomura Y, et al. Multicenter randomized comparison ofLigaSure versus conventional surgery for gastrointestinal carcinoma. Surg Today.2010;40(11):1050-4. doi:10.1007/s00595-009-4234-z. PMID:21046504

  • 39. Trilling B, Riboud R, Abba J, Girard E, et al. Energy vessel sealing systems versus mechanicalligature of the inferior mesenteric artery in laparoscopic sigmoidectomy. Int J Colorectal Dis.2016;31(4):903-8. doi:10.1007/s00384-016-2508-7. PMID:26841803

  • 40. Hubner M, Demartines N, Muller S, Dindo D, et al. Prospective randomized study ofmonopolar scissors, bipolar vessel sealer and ultrasonic shears in laparoscopic colorectalsurgery. Br J Surg. 2008;95(9):1098-104. doi:10.1002/bjs.6321. PMID:18690630

  • 41. Tou S, Malik AI, Wexner SD, Nelson RL. Energy source instruments for laparoscopiccolectomy. Cochrane Database Syst Rev. 2011;10.1002/14651858.CD007886.pub2(5):CD007886. doi:10.1002/14651858.CD007886.pub2.PMID:21563161

  • 42. Campagnacci R, de Sanctis A, Baldarelli M, Rimini M, et al. Electrothermal bipolar vesselsealing device vs. ultrasonic coagulating shears in laparoscopic colectomies: a comparativestudy. Surg Endosc. 2007;21(9):1526-31. doi:10.1007/s00464-006-9143-2. PMID:17287913

  • 43. Guerrieri M, Sanctis A, Baldarelli M, Nisi M, et al. Electrothermal bipolar energy-based devicein laparoscopic right colectomy: our experience. Minerva Chir. 2008;63(6):455-60.PMID:19078877

  • 44. Rimonda R, Arezzo A, Garrone C, Allaix ME, et al. Electrothermal bipolar vessel sealingsystem vs. harmonic scalpel in colorectal laparoscopic surgery: a prospective, randomizedstudy. Dis Colon Rectum. 2009;52(4):657-61. doi:10.1007/DCR.0b013e3181a0a70a.PMID:19404071