Gain Insight into Brain Response with BIS™ Technology([FOOTNOTE=Dershwitz M. Should we measure depth of anesthesia? Seminars in Anesthesia, Perioperative Medicine and Pain. 2001; 20(4) : 246-256.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=804982])

Bispectral Index™ (BIS™) monitoring enhances the clinician’s patient-targeted approach to induction, maintenance and emergence. BIS™ technology non-­invasively measures and interprets brain wave activity directly related to the effects of anesthetic agents:

  • Helps the clinician customize anesthetic dosing to individual patient physiologies
  • Indicates hypnotic effect through the easy-­to-­read BIS™ index
  • Facilitates improved patient outcomes as validated in multiple clinical studies([FOOTNOTE=Gan TJ, Glass PS, Windsor A, et al. Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil, and nitrous oxide anesthesia. BIS™ Utility Study Group. Anesthesiology. 1997; 87(4): 808-815.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35754]),([FOOTNOTE=Punjasawadwong Y, Boonjeungmonkol N, Phongchiewboon A. Bispectral index for improving anaesthetic delivery and postoperative recovery. Cochrane Database of Systematic Reviews. 2007; 17(4): CD003843.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=185841]),([FOOTNOTE=White PF, Ma H, Tang J, Wender RH, Sloninsky A, Kariger R. Does the use of electroencephalographic bispectral index or auditory evoked potential index monitoring facilitate recovery after desflurane anesthesia in the ambulatory setting? Anesthesiology. 2004;100(4): 811-817.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35731]),([FOOTNOTE=Myles PS, Leslie K, McNeil J, Forbes A, Chan MT. Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial. Lancet. 2004 ; 363(9423) : 1757-1763.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35729]),([FOOTNOTE=Avidan MS, Zhang L, Burnside BA, et al. Anesthesia awareness and the bispectral index. N Engl J Med. 2008;13;358(11) : 1097-1108.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=185918]),([FOOTNOTE=Avidan MS, Mashour GA. Prevention of intraoperative awareness with explicit recall: making sense of the evidence. Anesthesiology. 2013; 118(2): 449 - 456.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=301466]),([FOOTNOTE=Ekman A, Lindholm ML, Lennmarken C, Sandin R. Reduction in the incidence of awareness using BIS™ monitoring. Acta Anaesthesiol Scand. 2004; 48(1): 20-26.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=117525]),([FOOTNOTE=Luginbühl M, Wüthrich S, Petersen-Felix S, Zbinden AM, Schnider TW. Different benefit of bispectal index (BIS™) in desflurane and propofol anesthesia. Acta Anaesthesiol Scand. 2003; 47(2): 165-173.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35736])

BIS™ Brain Monitoring

Confidently monitor and tailor safe, optimal anaesthesia for each patient with BIS™ brain monitoring.

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Order Information

How to Order

For additional information or to place an order, call Customer Service at +44 (0) 19 2320 2504.

Order Information
Order Code Description Unit of Measure Quantity
186-1014 BIS™ Complete 4-Channel Monitoring System Each 1
186-0224-AMS BIS™ LOC 4-Channel Monitor with Patient Interface Cable (PIC-4) Each 1
186-0212 BIS™ Bilateral Sensor Each 1
Parameters BIS, SQI, EMG, SR, BC, TP, SEF, EEG
Trended parameters BIS, SQI, EMG, SR, BC, SEF
BIS™ alarm upper and lower limit, results in visual and audible alert when out of range

Product Features

The BIS™ Complete 4-­channel monitor translates the raw EEG data into the easy-­to-­read BIS™ index.

The monitor provides:

  • User-­configurable display
  • Versatile platform for future expandability
  • Four-­channel EEG monitoring
  • Asymmetry Indicator (ASYM)
  • Ability to trend BIS-­Left and BIS-­Right values

Product Technology

BIS™ monitoring technology provides valuable information about the status of your patients to help address each their unique anaesthetic requirements.

BIS™ technology offers the clinician added security for providing specialised critical care and comfort for their patients, including those who may be more sensitive to the haemodynamic effects of anaesthesia.

BIS™ monitoring provides invaluable information about patient status to help clinicians address their unique anaesthetic requirements. This may be particularly valuable for:

  • Patients with complex conditions whose status may suddenly or frequently change
  • Patients with cardiovascular conditions
  • Obese patients
  • Trauma patients or others requiring reduced levels of anaesthesia
  • BIS™ monitoring technology enables clinicians to manage anaesthetic goals of hypnosis, analgesia and immobility.
  • BIS™ monitoring technology enables clinicians to assess consciousness and sedation separately from cardiovascular reactivity.
    • Reduce emergence and recovery time2
    • Reduce anaesthetic drug use2
    • Reduce the risk of awareness during surgery5,8


"BIS™ monitoring is recommended as an option for all patients receiving total intravenous anaesthetic (TIVA). BIS™ technology is also cost effective in this patient population due to the inability to measure end-tidal anaesthetic concentration."([FOOTNOTE=National Institute for Health and Clinical Excellence. Depth of anaesthesia monitors (E-Entropy, BIS™ and Narcotrend) (DG6). November 2012. Available at:],[ANCHOR=],[LINK=])

– National Institute for Health and Clinical Excellence