Bispectral Index™ (BIS™) Monitoring System

Bispectral Index™ (BIS™) monitoring enhances the clinician’s patient-targeted approach to induction, maintenance, and emergence. BIS™ technology non-invasively measures and interprets brain wave activity directly related to the effects of anesthetic agents.

Among other benefits, BIS™ technology:

• Helps the clinician customize anesthetic dosing to individual patient physiologies
• Indicates hypnotic effect through the easy-to-­read BIS™ index
• May be associated with improved patient outcomes as validated in multiple clinical studies([FOOTNOTE=Gan TJ, Glass PS, Windsor A, et al. Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil, and nitrous oxide anesthesia. BIS Utility Study Group. Anesthesiology. 1997;87(4):808-815.],[ANCHOR=View Abstract],[LINK=https://www.medtronic.com/covidien/en-us/support/clinical-evidence.html?id=35754])^,([FOOTNOTE=Punjasawadwong Y, Boonjeungmonkol N, Phongchiewboon A. Bispectral index for improving anaesthetic delivery and postoperative recovery. Cochrane Database of Systematic Reviews. 2007;17(4):CD003843.],[ANCHOR=View Abstract],[LINK=https://www.medtronic.com/covidien/en-us/support/clinical-evidence.html?id=185841])^,([FOOTNOTE=White PF, Ma H, Tang J, Wender RH, Sloninsky A, Kariger R. Does the use of electroencephalographic bispectral index or auditory evoked potential index monitoring facilitate recovery after desflurane anesthesia in the ambulatory setting? Anesthesiology. 2004;100(4):811-817.],[ANCHOR=View Abstract],[LINK=https://www.medtronic.com/covidien/en-us/support/clinical-evidence.html?id=35731])^,([FOOTNOTE=Myles PS, Leslie K, McNeil J, Forbes A, Chan MT. Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial. Lancet. 2004;363(9423):1757-1763.],[ANCHOR=View Abstract],[LINK=https://www.medtronic.com/covidien/en-us/support/clinical-evidence.html?id=35729])^,([FOOTNOTE=Avidan MS, Zhang L, Burnside BA, et al. Anesthesia awareness and the bispectral index. N Engl J Med. 2008;13;358(11):1097-1108.],[ANCHOR=View Abstract],[LINK=https://www.medtronic.com/covidien/en-us/support/clinical-evidence.html?id=185918])^,([FOOTNOTE=Avidan MS, Mashour GA. Prevention of intraoperative awareness with explicit recall: making sense of the evidence. Anesthesiology. 2013;118(2):449-456.],[ANCHOR=View Abstract],[LINK=https://www.medtronic.com/covidien/en-us/support/clinical-evidence.html?id=301466])^,([FOOTNOTE=Ekman A, Lindholm ML, Lennmarken C, Sandin R. Reduction in the incidence of awareness using BIS monitoring. Acta Anaesthesiol Scand. 2004;48(1):20-26.],[ANCHOR=View Abstract],[LINK=https://www.medtronic.com/covidien/en-us/support/clinical-evidence.html?id=117525])^,([FOOTNOTE=Luginbühl M, Wüthrich S, Petersen-Felix S, Zbinden AM, Schnider TW. Different benefit of bispectal index (BIS) in desflurane and propofol anesthesia. Acta Anaesthesiol Scand. 2003;47(2):165-173.],[ANCHOR=View Abstract],[LINK=https://www.medtronic.com/covidien/en-us/support/clinical-evidence.html?id=35736])

Brain monitoring is an adjunctive technology that should not be used as the sole basis for diagnosis or clinical decision-making.