You want the best outcomes for your patients. So, delivering just the right dose of anesthetic agent to personalize care is essential.
In a simple, configurable interface, the completely redesigned BIS™ Advance monitor helps you personalize anesthesia dosing to improve patient outcomes and support faster recovery.
Using less anesthesia can lead to faster extubation and faster discharge from the PACU for optimized patient throughput and a more efficient workflow.1
Simple to read — large, high-resolution touchscreen monitor
See the information you want — configurable data and settings
Quickly review readings — color-coordinated data
Use up to 38% less anesthetic agents to help control cost.1–5
Patients monitored with BIS™ technology wake up 27-53% faster in the OR.1,3,5,6
Patients monitored with BIS™ technology are 87% more fully awake and oriented upon arrival in the PACU and ready for discharger faster.1,5
"The pooled data showed that the use of BIS was significantly associated with a lower incidence of POCD and improved recovery parameters (extubation time, time to eye opening, and time to discharge from the PACU)."
– Wei Zhuen Chew et al, Bispectral Index (BIS) Monitoring and Postoperative Delirium in Elderly Patients Undergoing Surgery: A Systematic Review and Meta-Analysis With Trial Sequential Analysis
Chew WZ, Teoh WY, Sivanesan N, San Loh P, Shariffuddin II, Ti LK, Ng KT. Bispectral index (BIS) monitoring and postoperative delirium in elderly patients undergoing surgery: A systematic review and meta-analysis With trial sequential analysis. Journal of Cardiothoracic and Vascular Anesthesia. 2022 Dec 1;36(12):4449–59.
"We found that BIS monitoring of the depth of anesthesia prevented POD, whereas EEG monitoring was not effective. BIS quantifies the depth of anesthesia based on EEGs, which enables a more accurate control of anesthetic concentration and increases patient safely."
– Xia Li et al, Effects of perioperative interventions for preventing postoperative delirium
Li X, Wang Y, Liu J, Xiong Y, Chen S, Han J, Xie W, Wu Q. Effects of perioperative interventions for preventing postoperative delirium: A protocol for systematic review and meta-analysis of randomized controlled trials. Medicine. 2021 Jul 7;100(29)
"…in intravenous anesthesia, BIS monitoring could reduce the incidence of intraoperative awareness by approximately 80%."
– Wen-Wei Gao, et al., in a clinical review on BIS monitoring on interoperative awareness
Gao, Ww., He, Yh., Liu, L. et al. BIS Monitoring on Intraoperative Awareness: A Meta-analysis. Curr Med Sci. 38, 349–353 (2018). https://doi.org/10.1007/s11596-018-1886-1
The BIS™ monitoring system should not be used as the sole basis for diagnosis or therapy and is intended only as an adjunct in patient assessment. Reliance on the BIS™ monitoring system alone for intraoperative anesthetic management is not recommended.
1. Lewis SR, Pritchard MW, Fawcett LJ, Punjasawadwong Y. Bispectral index for improving intraoperative awareness and early postoperative recovery in adults. Cochrane Database System Review. 2019;9:CD003843. doi:10.1002/14651858.CD003843.pub4.
2. Punjasawadwong Y, Phongchiewboon A, Bunchungmongkol N. Bispectral index for improving anaesthetic delivery and postoperative recovery. Cochrane Database Syst Rev. 2014;(6):CD003843. doi:10.1002/14651858.CD003843.pub3.
3. Song D, Joshi GP, White PF. Titration of volatile anesthetics using bispectral index facilitates recovery after ambulatory anesthesia. Anesthesiology. 1997;87(4):842–848.
4. Luginbühl M, Wüthrich S, Petersen-Felix S, Zbinden AM, Schnider TW. Different benefit of bispectal index (BIS) in desflurane and propofol anesthesia. Acta Anaesthesiol Scand. 2003;47(2):165–73. ncbi.nlm.nih.gov/pubmed/12631045.
5. Gan TJ, Glass PS, Windsor A, et al. Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil and nitrous oxide anesthesia. Anesthesiology. 1997;87(4):808–815. doi:10.1097/00000542-199710000-00014.
6. Wong J, Song D, Blanshard H, Grady D, Chung F. Titration of isoflurane using BIS index improves early recovery of elderly patients undergoing orthopedic surgeries. Can J Anaesth. 2002;49(1):13–18. doi:10.1007/BF03020413.