Intelligent surgical stapling — a wise choice
Experience the intelligent Signia™ stapling system — a powered surgical stapler equipped with Adaptive Firing™ and Adaptive Compression™ technologies. By providing real-time feedback across linear and circular stapling applications,1,2,3 the Signia™ stapling system gives you the confidence of consistent, precisely formed staple lines.†,4,5 And with a versatile array of reloads backed by the benefits of Tri-Staple™ technology, Signia™ staplers are adaptable to the needs of you and your patients.

Intelligence
Experience the intelligence of the Signia ™ stapling system — the powered surgical stapler that senses tissue thickness and adjusts clamping force and firing speed in real time.†,4,6

Confidence
Intelligence drives Signia™ stapling — and Signia™ stapling drives Tri-Staple™ technology. The result is secured staple lines that you and your patients can depend on.†,‡,7,8

Versatility
By offering a powered handle with easy-to-reach push-button controls§,9,10 plus a range of adapters and reloads to fit your specific needs, the intelligent Signia™ stapling system is adaptable to your cases — and you.
A surgical stapler with firing that adapts at your command
The Signia™ stapling system provides an intelligent,5,6 fully powered surgical stapling solution for enhanced precision and maneuverability.◊ ,11
Enhance your staple lines†,4,6
Sensing technology: The Signia™ system senses targeted tissue†,1,4,7 and measures the forces applied during clamping and firing,†,1,4,7 providing real-time feedback so you can make informed decisions about reload selection.¶,12
Ease of use: An easy-to-read display screen#,10 plus easy-to-reach controls§,10 that can all be operated with one hand§,10
Tri-Staple™ technology: Deploy three rows of varied-height staples for superior staple line strength and leak resistance,¶,∆,13,14 as well as enhance perfusion into the staple line∞,15

The Signia™ stapling system is ready to support you and your patients across a variety of procedures.

Signia™ linear stapler with Tri-Staple™ technology
Explore an array of linear stapling adapters and reloads, all powered by Signia™ intelligence and Tri-Staple™ performance.
Our diverse array of Tri-Staple™ reloads are designed for a variety of applications and surgical specialties.

Tri-Staple™ 2.0 30 mm reload
The Tri-Staple™ 2.0 30 mm reload is a short reload used in situations where space is limited.

Tri-Staple™ 2.0 black reload
The Tri-Staple™ 2.0 black intelligent reload is designed to address thick tissue.

Tri-Staple™ 2.0 curved tip reload
The Tri-Staple™ 2.0 curved tip intelligent reload is designed to provide visibility and maneuverability around target tissues and vessels.

Tri-Staple™ 2.0 reinforced reload
Tri-Staple™ 2.0 reinforced intelligent reloads are endoscopic staplers with preloaded tissue reinforcement.
Meet clinical challenges with confidence
Surgical specialties have unique challenges and the Signia™ stapling system is designed to address them with a combination of technological intelligence and Tri-Staple™ performance.

Bariatric surgery
Tackle variable tissue with confidence
In bariatric surgery, a strong staple line is crucial to minimizing complications. With advanced design features, reloads with Tri-Staple™ technology deliver enhanced performance across a broad range of thicknesses.†,††,13,16-19

Colon and rectal surgery
Enhanced blood flow,∞,19 enhanced confidence
Enhancing blood supply to the anastomotic site is crucial in reducing the risk of anastomotic leaks. Tri-Staple™ technology’s graduated compression profile and varied height staples allow advanced perfusion into the staple line.∞,15,19

Thoracic surgery
Manage stress, increase confidence
In the challenging high-pressure environment of the OR, thoracic surgeons need to be confident that they can handle any challenge.
Tri-Staple™ technology provides enhanced strength and leak resistance¶,#,∆ ,13,14,16,20 while generating reduced stress on tissue during compression and clamping.∞,‡‡ ,16,20
Uniting to advance surgical specialties
Our advanced instruments and digital technologies support surgeries across various specialties and modalities, allowing surgical teams to focus on delivering exceptional outcomes.

Bariatric surgery
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Colon and rectal surgery
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Thoracic surgery
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† Preclinical results may not correlate with clinical performance in humans.
¶ Bench test results may not necessarily be indicative of clinical performance.
†† Bench test results may not necessarily be indicative of clinical performance.
References
PT00002451 Signia™ Stapler User Manual Page 13
Signia™ stapler [user manual]. North Haven, CT: Medtronic; 2023.
Based on report #RE00052285 rev W, Gen II Power Pack EEA™ stapler application SRS. Oct 2023.
Based on internal test report #R2146-151-0, Powered stapling firing speed DOE analysis and ASA parameters. 2015.
Based on internal report # RE00026887, Signia™ stapling system 510(k) report. 2016
Based on internal test report #R2146-173-0, ASA verification testing with slow speed force limit evaluation.
Based on internal report #RE00218740, Signia™ stapling adaptive firing technology data calculations and references. Aug. 7, 2019.
Based on internal test report #RE00147607, 4.5 mm round staple pull-apart analysis report. 2018.
Based on internal test report #RE00174815 rev 1, Software settings for monitoring tissue relaxation. Oct 2021.
Based on internal test report #RE00024826 rev D, Signia™ stapling system summative usability report. September 2016.
Based on internal report #R0033554, iDrive™ Ultra stapler PCR summary report. November 2012.
Based on internal test report #PCG-001, Tyvek pull-apart test comparing Echelon™* and Tri-Staple™ technology. March 2011.
Based on internal test report #PCG-002, In-vitro leak comparison. March 08,2011.
Based on internal test report #2128-002-2, Final analysis of staple-line vascularity using MicroCT. July 2015
Based on internal test report #PCG-018, 2-D FEA of linear staplers. November 2012.
Based on internal test report #PCG-004, Undercrimp comparisons in increasing pads of foam between Echelon™* and Tri-Staple™ technology. January 2012.
Based on internal test report #PCG-006, Staple formation comparison between Medtronic EGIA60AXT and Ethicon ECR60G in an ex-vivo tissue model. January 2012.
Based on internal test report #PCG-019, Comparative test of Endo GIA™ stapler using black reloads with Tri-Staple™ technology and Ethicon Echelon Flex™* black reloads. June 2014.
Based on internal test report #PCG-007 rev 1, Perfusion into Clamped Media. Sept. 2, 2011.