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ODDS ARE, IT CAN'T WAIT.

Be there for them. Ask your doctor if your chronic reflux could be putting your health and your life at risk.
See if you might be at risk

DON’T TAKE CHANCES, TAKE CHARGE

Years of chronic reflux can lead to Barrett’s esophagus, a precursor to esophageal cancer.1 Over time, a constant backwash of stomach acid causes the lining of the esophagus to change. Since there are no obvious symptoms, it’s possible to develop precancerous Barrett’s esophagus or esophageal adenocarcinoma without knowing it.1

  • It’s estimated that as many as 20% of adults suffer from symptomatic reflux.2,6
  • Gastroesophageal reflux disease (GERD) develops when contents of the stomach reflux into the esophagus, which causes symptoms of heartburn and/or regurgitation.3
  • GERD is one of the most important risk factors for the development of Barrett’s,4 a premalignant form of esophageal adenocarcinoma (EAC).

What is Barrett's Esophagus? - (01:39)

Understand the progression of GERD to Barrett's esophagus and learn how to reduce your risk.
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UNDERSTAND THE RISK FACTORS

A variety of factors may contribute to increased risk for disease progression, including:5

  • 5+ years of GERD
  • Over age 50
  • Caucasian
  • Male
  • Smoker
  • Family history
  • Obesity
UNDERSTAND YOUR RISK

Thumbnail image of the Barret's Esophagus risk assessment

HEARTBURN CAN BE HEREDITARY

While prevalence of Barrett’s esophagus is low in the general population, it’s higher in GERD patients.1

  • Up to 15% of GERD patients may develop Barrett’s.6
  • Having a family history of Barrett’s or esophageal adenocarcinoma may increase risk by 5x.7

ADAM’S STORY

"My father passed away from Esophageal cancer."

HEAR ADAM’S STORY - (02:33)

IT PAYS TO BE PROACTIVE

If you’ve been diagnosed with Barrett’s, odds are, it can’t wait. Talk to your GI about treatment options.

Harry’S STORY

"I didn’t realize what reflux was doing to my esophagus."

HEAR HARRY’S STORY - (03:54)

ERADICATE BARRETT’S TO REDUCE CANCER RISK

If you have Barrett’s, watching and waiting isn’t always effective because the disease can progress quickly between endoscopy appointments.8, 9

Talk to your GI about a more proactive approach:

  • Studies show that treatment with radiofrequency ablation can reduce the relative risk of Barrett’s progressing to esophageal adenocarcinoma by up to 94%.*10
ACCESS PATIENT RESOURCES

Why Choose Radiofrequency Ablation? - (02:23)

Understand how radiofrequency ablation (RFA) treatments can significantly reduce risk of progression to esophageal cancer.
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Barrx™ radiofrequency ablation system
Risk Information
The following are transient side effects that may be expected after treatment: chest pain, difficulty swallowing, painful swallowing, throat pain, and/or fever.
Potential complications include mucosal laceration, minor or major bleeding, endoscopic clipping to manage mucosal laceration or bleeding, perforation of the stomach, esophagus or pharynx, surgery to manage perforation, esophageal stricture, endoscopic dilation to manage stricture, pleural effusion, transfusion secondary to major bleeding, cardia arrhythmia, aspiration, infection and death.

THE BEST
PROTECTION IS
EARLY DETECTION

If you’ve been living with chronic reflux for years, talk to your doctor. 

Find a Doctor
*

94% is the calculated relative risk reduction [ (26-1.5)/26] = 25/26 *100. From [25.0% (1.5% for ablation vs 26.5% for control; 95% CI, 14.1%-35.9%; P < .001]

1

Dam AN, Klapman J. A narrative review of Barrett’s esophagus in 2020, molecular and clinical update. Annals of translational medicine. 2020;8(17):1107.

2

Dent J, El-Serag HB, Wallander MA, et al. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 2005;54:710-7.

3

Labenz J, Chandrasoma PT, Knapp LJ, DeMeester TR. Proposed approach to the challenging management of progressive gastroesophageal reflux disease. World journal of gastrointestinal endoscopy. 2018;10(9):175-183.

4

Spechler SJ, Souza RF. Barrett’s esophagus. N Engl J Med 2014;371:836-45.

5

Muñoz-Largacha JA, Fernando HC, Litle VR. Optimizing the diagnosis and therapy of Barrett’s esophagus. Journal of thoracic disease. 2017;9(Suppl 2):S146-S153.

6

Schlottmann F, Patti MG. Shaheen NJ. From heartburn to Barrett’s esophagus, and beyond. World journal of surgery. July 2017:
1698-1704.

7

Tofani C, et al. Abstract 69. Presented at: World Congress of Gastroenterology at American College of Gastroenterology Annual Scientific Meeting; Oct. 13–18, 2017; Orlando, FL.

8

Fleischer DE et al. The case for endoscopic treatment of non-dysplastic and low-grade dysplastic Barrett’s esophagus. Dig Dis Sci 2010; 55(7):1918-31.

9

Wolf WA, Pasricha S, Cotton C, et al. Incidence of Esophageal Adenocarcinoma and Causes of Mortality after Radiofrequency Ablation of Barrett's esophagus. Gastroenterology. 2015;149:1752-1761.

10

Phoa KN, van Vilsteren FG, Pouw RE, Weusten BL, Bisschops R, Schoon EJ, et al. Radiofrequency ablation vs. endoscopic surveillance for patients with Barrett’s esophagus and low-grade dysplasia: A randomized clinical trial. JAMA. 2014 Mar 26;311(12): 1209-17.