BRAINSENSE™ TECHNOLOGY

Unprecedented Insights Inside and Outside the Clinic



Download our clinical compendium to find scientific
publications supporting the use of local field potentials
(LFPs) as signals of interest in DBS therapy.

DOWNLOAD CLINICAL COMPENDIUM

What is it

BrainSense™ technology* is designed to capture a patient's brain signals, providing clinicians objective data directly from a DBS patient's brain to understand the impact of treatment decisions such as medication or stimulation changes.

Dr. Mark Richardson explains what BrainSense™ technology can do for clinicians.
More information (see more) Less information (see less)

HOW IT WORKS

BrainSense™ technology captures brain signals (local field potential, or LFP) using the implanted DBS lead. These signals can be recorded simultaneously while delivering therapeutic stimulation, inside and outside the clinic. Clinicians can also correlate these brain signals with stimulation and patient-captured events such as medication, symptoms, or side effects.

Watch the animation to learn more about how BrainSense™ technology works.
More information (see more) Less information (see less)

Managing Patient Treatment Is Complex. Brain Signals Can Help.

PARKINSON'S SYMPTOMS ARE DYNAMIC

Both medications and DBS therapy impact Parkinson's symptoms, and these therapies can interact in unpredictable ways.

Today, clinicians have a limited view how patient symptoms fluctuate in their daily lives since common out-of-clinic assessment tools (e.g., motor diaries) have limitations.

need

BRAIN SIGNALS CONTAIN VALUABLE INFORMATION

Brain signals have been shown to correlate with Parkinson's symptoms (akinesia, rigidity) as well as with medication and DBS stimulation.

need
alt

TRACK PATIENT'S BRAIN STATE

As a result, brain signals can provide clinicians unprecedented insights into a patient’s symptom state fluctuations and help deliver personalized, data-driven therapy.
 

QUANTIFY BRAIN STATE FLUCTUATIONS

Clinicians can also quantify brain state fluctuations by defining signal thresholds that correspond to patient state (symptoms or side effects); and use this information to track patient state across visits and maximize time spent in ideal brain state (e.g., ON state vs. OFF state).*
 

Percept PC Clinician programmer showing a data summary of thresholds using a bar graph.
*

The sensing feature of the Percept™ PC system is intended for use in patients receiving DBS where chronically-recorded bioelectric data may provide useful, objective information regarding patient clinical status.  Clinical benefits of brain sensing have not been established. 

Signals may not be present or measurable in all patients. Clinical benefits of brain sensing have not been established.

1

Medtronic DBS Therapy for Parkinson's Disease and Essential Tremor Clinical Summary, 2015.

2

Neumann W-J, Kuhn A. Subthalmic beta power-unified Parkinson's disease rating scale III corelations require akinetic symptoms. Mov Discord. 2017 Jan;32(1):175-176.

3

Ozturk M, Abosch A, Francis D, Wu J, Jimenez-Shahed J, Ince NF. District subthalamic coupling in the ON state describes motor performance in Parkinson's disease. Mov Disord. 2020;35:91-100.

4

Unpublished data, External Research Study. Courtesy: Helen Bronte-Stewart, MD, MS, John E. Cahill Family Professor, Professor of Neurology at the Stanford University Medical Center.