Man and woman eating dinner. The man grasps at chest while experiencing acid reflux pain.

YOUR HEARTBURN MAY NOT BE HARMLESS

Don’t ignore the signs. Without treatment, heartburn could progress to a form of esophageal cancer.1,2
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Infographic depicting the risk of esophageal cancer in Barrett's esophagus patients.

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Information and resources on this site should not be used as a substitute for medical advice from your doctor. Always discuss diagnosis and treatment information including risks with your doctor. Keep in mind that all treatment and outcome results are specific to the individual patient. Results may vary.


1

Phoa KN, van Vilsteren FG, Weusten BL, Bisschops R, Schoon EJ, Ragunath K, et al. Radiofrequency ablation vs endoscopic surveillance for patients with Barrett esophagus and low-grade dysplasia: a randomized clinical trial. JAMA. 2014;311(12)1209-17.

2

Shaheen NJ, et al. Radiofrequency ablation in Barrett’s esophagus with dysplasia. N Engl J Med 2009, 360:2277-88 

3

Vaezi M, Zehrai A, Yuksel E. Testing for refractory gastroesophageal reflux disease. ASGE Leading Edge. 2012;2(2):1-13. American Society Gastroenterology Endoscopy, Pages 1-4.

4

Bollschweiler E, Knoppe K, Wolfgarten E, Hölscher AH. Prevalence of dysphagia in patients with gastroesophageal reflux in Germany. Dysphagia. 2008;23(2):172-176. doi:10.1007/s00455-007-9120-5.

5

Patcharatrakul T, Gonlachanvit S. Gastroesophageal reflux symptoms in typical and atypical GERD: Roles of gastroesophageal acid refluxes and esophageal motility. Journal of Gastroenterology & Hepatology. 2014;29(2):284-290. doi:10.1111/jgh.12347.

6

Dymedex Market Development Consulting, GERD Sizing and Segmentation for pH Testing. February 13, 2015.

7

Dymedex Market Development Consulting, Strategic Market Assessment: Barrx-GI, October 30, 2014.

8

Wani S, Falk G, Hall M, Gaddam S, Wang A, Gupta N, et al. Patients with nondysplastic Barrett’s esophagus have low risks for developing dysplasia or esophageal adenocarcinoma. Clin Gastroenterol Hepatol. 2011;9(3):220-7.

9

SEER Cancer Statistics Factsheets: Esophageal Cancer. National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/statfacts/html/esoph.html (accessed December 2016).

10

Pohl H, Welch G et al. The role of over diagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence. J Natl Cancer Inst 2005;97:142-6.

11

SEER Cancer Statistics Animator, 1975-2012. National Cancer Institute. Bethesda, MD.