VenaSeal Closure System

A CLINICAL SOLUTION
VenaSeal
Closure System


IMMEDIATE CLOSURE
PATIENT COMFORT

METHOD OF ACTION

VenaSeal Procedure Step 1

The VenaSeal™  system proprietary cyanoacrylate-based adhesive safely and effectively closes the diseased vein segment.1,2

  • VenaSeal adhesive is delivered in 0.10 cc allotments along the length of the targeted vein segment.
  • The proprietary catheter is highly visible under ultrasound, for precise delivery of the adhesive.
  • The procedure can be completed in an office or hospital setting and requires no additional capital equipment.

THE RESULTS YOU HAVE COME TO EXPECT

VeClose 36-Month Results (IDE Clinical Trial)3

  • One of the largest multicenter, randomized prospective comparisons of superficial venous ablation technologies
  • No DVT, PE or adhesive-related allergies  were reported in the VenaSeal closure system study arm
  • 94.4% closure rate at 3 years

 

VeClose Study 36-Month Results

PATIENT COMFORT

Leg with varicose veins before and after VenaSeal procedure

The VenaSeal closure system procedure offers:

  • Rapid return to normal activities after treatment4,5
  • Minimized pain, tenderness and ecchymosis5
  • Significant improvements in quality of life6

The VenaSeal closure system procedure eliminates:1,2

  • Tumescent anesthesia
  • Thermal nerve injury
  • Post-procedure compression stockings*

*

Some patients may benefit from the use of compression stockings post-procedure.


1

Proebstle, T.M. The European Multicenter Study on Cyanoacrylate Embolization of Refluxing Great Saphenous Veins without Tumescent Anesthesia and without Compression Therapy. Results presented at: Charing Cross; 2016; London, UK. 

2

Almeida, J.I., Jacier, J.J., Mackay, E.G., Bautista, C., Cher, D.J. and Proebstle, T.M. Thirty-Sixth Month Follow-up of First-in-human Use of Cyanoacrylate Adhesive for Treatment of Saphenous Vein Incompetence. J Vasc Surg: Venous and Lymphatic Disorders. 2017. Published Online: 2 June 2017.

3

Morrison, N. VenaSeal Closure System vs. Radiofrequency Ablation for Incompetent Great Saphenous Veins (VeClose). 36-Month Results presented at: IVC; April 20,2017; Miami, FL.

4

Gibson K. Cyanoacrylate Closure of Incompetent Great, Small and Accessory Saphenous Veins without the use of Post-Procedure Compression: A Post-Market Evaluation of the VenaSeal System (WAVES trial): Twelve Month Data. Results presented at: Charing Cross; 2017; London, UK. 

5

Morrison, N., Gibson, K., McEnroe, S., Goldman, M., King, T., Weiss, R., Cher, D., Jones, A. Randomized Trial Comparing Cyanoacrylate Embolization and Radiofrequency Ablation for Incompetent Great Saphenous Veins (VeClose). J Vasc Surg. 2015;61(4):985–994. 

6

Morrison, N., et al. VeClose Trial 12-month Outcomes of Cyanoacrylate Closure Versus Radiofrequency Ablation for Incompetent Great Saphenous Veins. J Vasc Surg.  http://dx.doi.org/10.1016/j.jvsv.2016.12.005.