Gastroesophageal reflux disease (GERD) is a serious condition. The lifetime risk of progression from GERD to Barrett's esophagus is 26.5%.1 Progression of Barrett’s esophagus to esophageal adenocarcinoma (EAC) can be deadly. Patients with first-degree family history of EAC are 5.5 times more likely to progress from Barrett’s to EAC.3 For every one-centimeter increase in Barrett’s esophagus length, a patient experiences a 28% increase in risk of progression to EAC or high-grade dysplasia (HGD).2
Learn about identifying risk factors in Barrett's esophagus.
Proactively reduce the risk of Barrett’s esophagus progression with radiofrequency ablation.4-6 RFA can eradicate Barrett’s esophagus and reduce the relative risk of disease progression to HGD/EAC by up to 94%.7
Dymedex Market Development Consulting, GERD Sizing and Segmentation for pH Testing, February 13, 2015.
Anaparthy R, Gaddam S, Kanakadandi V, et al. Association between length of Barrett’s Esophagus and risk of high-grade dysplasia or adenocarcinoma in patients without dysplasia. Clin Gastroenterol Hepatol. 2013;11(11):1430-6.
Tofani C, Gandhi K, Spataro J, et al. Esophageal adenocarcinoma in a first degree relative increases risk for progression to esophageal adenocarcinoma in patients with Barrett’s Esophagus. Am J Gastroenterol. 2017; Abstract 309:112(1)
ShaheenNJ, Sharma P, et al. Radiofrequency ablation in Barrett's esophagus with dysplasia. N Engl J Med. 2009 May 28;360(22):2277-2288
Phoa KN, van Vilsteren FG, Pouw RE, Weusten BL, et al. Radiofrequency ablation vs endoscopic surveillance for patients with Barrett esophagus and low-grade dysplasia: a randomized clinical trial. JAMA. 2014 Mar 26;311(12):1209-17
Wolf WA, Lightdale CJ, Li N, et al. Incidence of Esophageal Adenocarcinoma (EAC) in Patients with Barrett’s Esophagus (BE) Undergoing Radiofrequency Ablation. Gastroenterology 2015 Aug 28.(15)1245-7
Phoa K, van Vilsteren FGI,Weusten BLAM, Bisschops R, Schoon EJ, Ragunath K, et al. Radiofrequency Ablation vs Endoscopic Surveillance for Patients With Barrett Esophagus and Low-Grade Dysplasia: A Randomized Clinical Trial. JAMA. 2014;311(12) 1209-1217. doi:10.1001/jama.2014.2511.
Images do not represent all components of the system.