IN.PACT™ Admiral™ drug-coated balloon (DCB) has proven, long-term durable outcomes across multiple clinical trials, as well as across complex patient and lesion types. This strong clinical data may be explained by the mechanism of action.
Without a permanent scaffold, DCB must transfer drug to the tissue in a manner that enables a long-term effect on restenosis.
1. Solid-phase drug delivery
IN.PACT Admiral DCB delivers solid-phase paclitaxel to the vessel, establishing reservoirs of drug
2. Sustained drug availability
These reservoirs provide a source of soluble drug which is available to exert an anti-proliferative effect on tissue
3. Prolonged anti-proliferative effect
With extended drug availability, the anti-proliferative effect of paclitaxel is prolonged
Representative micrograph 28 days post drug delivery.1
Data on file at Medtronic.