Graphic illustrating that 1 in 3 adults worldwide suffer from hypertension (HTN).

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HYPERTENSION AFFECTS BILLIONS

The scale of the hypertension epidemic is difficult to overstate. Affecting approximately 20% of men and 25% of women, hypertension is one of the most pervasive medical conditions in the world.1

Illustrated pressure gauge pointing to "high," signifying that hypertension is a global epidemic affecting billions around the world.

NON-ADHERENCE IS A CHALLENGE

One of the most common treatments for hypertension is medication. Patients often take as many as three or more daily medications, each of which may cause a range of unpleasant side effects. In fact, nonadherence doubles when patients move from two to three drugs.2,3,4

THE RISKS ARE REAL

Uncontrolled hypertension is the single largest contributor to death and remains a major health burden that dramatically increases the risk of heart attack, stroke, and heart and kidney failure.5,6,7

45% of deaths due to heart disease 51% of deaths due to stroke

COSTS ARE INCREASING

The annual costs of treating hypertension are expected to triple. Adults with hypertension spend 3.2x more on medical care.8

$200 BILLION By 2030 in the U.S. alone

LEARN ABOUT THE UNMET NEED

Hypertension is a global epidemic that requires more focus.

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1

World Health Organization. Hypertension fact sheet. 13 September 2019. https://www.who.int/news-room/fact-sheets/detail/hypertension

2

Hutchins R, Viera AJ, Sheridan SL, Pignone MP. Quantifying the utility of taking pills for cardiovascular prevention. Circ Cardiovasc Qual Outcomes. March 2015;8(2):155-163.

3

Gupta P, Patel P, Štrauch B, et al. Risk Factors for Nonadherence to Antihypertensive Treatment. Hypertension. June 2017;69(6):1113-1120.

4

Li J, Zheng H, Du HB, et al. The multiple lifestyle modification for patients with prehypertension and hypertension patients: a systematic review protocol. BMJ Open. August 14, 2014;4(8):e004920.

5

Whelton PK, Carey RM, Aronow WS et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart

6

Association Task Force on Clinical Practice Guidelines. Hypertension. 2018 Jun;71(6):1269-1324. doi: 10.1161/HYP.0000000000000066. Epub 2017 Nov 13. The World Health Report 2002: Reducing Risks, Promoting Healthy Life. Available at: http://www.who.int/whr/2002/en/ Last accessed July 2018.

7

Messerli FH, Williams B, Ritz E. Essential Hypertension. Lancet. 2007 Aug 18;370(9587):591-603.

8

HCCI research. 2018