CLINICAL EVIDENCE ClosureFast Procedure

Demonstrated long-term effectiveness

CLOSUREFAST LONG-TERM STUDY WITH 5-YEAR FOLLOW-UP

The only radiofrequency ablation system with 5-year published clinical evidence

Proven Results

In a large, multi-center, prospective trial, the ClosureFast™ procedure, delivered by the ClosureFast catheter, demonstrated the following results at 5 years.1,2

  • 91.9% occlusion rate
  • 94.9% reflux-free rate
3 Months 6 Months 1 Year 2 Years 3 Years 5 Years

Vein Occlusion

99.7%

98.6%

96.3%

94.5

92.6%

91.9%

No Reflux

99.7%

99.3%

99%

94.5%

95.7%

94.9%

Proven Patient Recovery

The ClosureFast catheter demonstrated high success rates and long-lasting relief from pain in over 200 patients across 8 centers at 3 years:2*

  • CEAP (classification system): 74.1% showed improvement
  • Venous Clinical Severity Score (VCSS): reduction in mean score from 3.9 to 0.9 (p>0.05)
  • Pain: increase in percentage of patients free of pain from 41.1% to 98%

*

For 7 cm RF catheter.


1

Proebstle, T.M., Alm, B.J., Gockeritz, O., et al. Five-year Results from the Prospective European Multicentre Cohort Study on Radiofrequency Segmental Thermal Ablation for Incompetent Great Saphenous Veins. British Journal of Surgery. 2015;102:212-8.

2

Proebstle, T.M., Alm, B.J., Gockeritz, O., et al. Three Year European Follow-up Endovenous Radiofrequency Thermal Ablation of the Great Saphenous Vein With or Without Treatment of Calf Varicosities. J Vasc Surg. 2011;54(1)146-52.