Clinical Outcomes for General Surgery

In a study of 170 patients at the University of Pittsburgh Medical Center, Geller et al. reduced transfusion rates for liver resections to 3.5% when using Transcollation technology compared to published averages of 15-33% for large institutions.

In a study examining the rate of pancreatic fistula (PF) formation occurring following distal pancreatectomy in 62 patients, those cases that incorporated Transcollation technology experienced a 75% reduction in the PF rate compared to control (10% PF rate in the Transcollation arm vs. 36% PF rate in the control arm).

In a study of 22 open partial nephrectomies with hilar occlusion, data showed a 30-35% (p=0.07) reduction in blood loss in the 11 cases treated with Transcollation technology.

Geller DA, Tsung A, Maheshwari V et al. Hepatic resection in 170 patients using saline-cooled radiofrequency coagulation. HPB 2005; 7:208-213.

Urena R, Mendez F, Woods M et al. Laparoscopic partial nephrectomy of solid renal masses without hilar clamping using monopolar radio frequency device. J Urology 2004; 171(3):1054-6.

Sprunger J, Herrell SD. Partial laparoscopic nephrectomy using monopolar saline-coupled radiofrequency device: animal model and tissue effect characterization. J Endourology 2005; 19(4):513-9.

Blansfield JA, Rapp MM, Chokshi RJ et al. Novel method of stump closure for distal pancreatectomy with a 75% reduction in pancreatic fistula rate. J Gastrointest Surg 2012; 16(3):524-528.

Truty MJ, Sawyer MD, Que FG. Decreasing pancreatic leak after distal pancreatectomy: saline coupled radiofrequency ablation in a porcine model. J Gastrointest Surg 2007; 11(8):998-1007.

Ilbeigi P, Ahmed M, Szobota J et al. Open partial nephrectomy using saline-enhanced monopolar radiofrequency device: evaluation of novel surgical technique with TissueLink DS3.0 dissecting sealer. Urology 2005; 65(3):578-82.

Richter S, Kollmar O, Schuld J et al. Randomized clinical trial of efficacy and costs of three dissection devices in liver resection. British Journal of Surgery 2009; 96(6):593-601.

Pamecha V, Gurusamy KS, Sharma D et al. Techniques for liver parenchymal transection: a meta-analysis of randomized controlled trials. HPB 2009; 11(4):275-281.

El Moghazy WM, Hedaya MS, Kaido T et al. Two different methods for donor hepatic transection: cavitron ultrasonic surgical aspirator with bipolar cautery versus cavitron ultrasonic surgical aspirator with radiofrequency coagulator-a randomized controlled trial. Liver Transplantation 2009; 15(1):102-105.

Gnerlich JL, Ritter JH, Linehan DC, Hawkins WG et al. Saline-linked surface radiofrequency ablation: a safe and effective method of surface ablation of hepatic metastatic colorectal cancer. Annals of Surgery.2009; 250(1):96-102.

Lee KF, Wong J, Cheung YS, Lai P. Feasibility of liver resection without the use of the routine Pringle manoeuver: an analysis of 248 consecutive cases. HPB 2009; 11(4):332-338.

Palavecino M, Kishi Y, Chun YS, Brown DL et al. Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy: analysis of 1557 consecutive liver resections. Surgery 2010; 147(1):40-48.

Kaneko H, Otsuka Y, Tsuchiya M et al. Application of devices for safe laparoscopic hepatectomy. HPB 2008; 10(4):219-224.

Koffron AJ, Stein JA. Laparoscopic liver surgery: parenchymal transection using saline-enhanced electrosurgery. HPB 2008; 10(4):225-228.

McGahan JP, Khatri VP. Imaging findings after liver resection by using radiofrequency parenchymal coagulation devices: initial experiences. Radiology 2008; 247(3):896-902.

Wojdemann M, Riber C, Burcharth F. New liver surgery techniques. Few complications and more advantages?” Ugeskr Laeger 2008; 170(16):1342-5 (in Danish).

Xia F, Wang S, Ma K et al. The use of saline-linked radiofrequency dissecting sealer for liver transaction in patients with cirrhosis. Journal of Surgical Research 2008; 149(1):110-114.

Hutchins R, Bertucci M. Experience with TissueLink radiofrequency-assisted parenchymal division. Digestive Surgery 2007; 24(4):318-321.

Nissen N, Grewal N, Lee J et al. Completely laparoscopic nonanatomic hepatic resection using saline-cooled cautery and hydrodissection. The American Surgeon 2007; 73(10):987-90.

Poon RT. Current techniques of liver transection. HPB 2007; 9(3):166-173.

Truty MJ, Sawyer MD, Que FG. Decreasing pancreatic leak after distal pancreatectomy: saline-coupled radiofrequency ablation in a porcine model. Journal of Gastrointestinal Surgery 2007; 11(8):998-1007.

Itamoto T, Fukuda S, Tashiro H et al. Radiofrequency-assisted partial splenectomy with a new and simple device.” The American Journal of Surgery 2006; 192(2):252-254.

Learn P, Bowers S, Watkins K. Laparascopic hepatic resection using saline-enhanced electrocautery permits short hospital stays. Journal of Gastrointestinal Surgery 2006; 10(3):422-7.

McCormack L, Petrowsky H, Clavien PA. Novel approach using dissecting sealer for uncinate process resection during pancreaticoduodenectomy. Journal of the American College of Surgeons 2006; 202(3):556-8.

Passariello M, Almenrader N, Coccetti B. Hyperthermia during surgery with TissueLink. Paediatric Anaesthesia 2006; 16(10):1099-1100.

Richtmyer, JM. Electrosurgical burns in pediatric patients undergoing liver resection with saline-enhanced radiofrequency technology. AORN Journal 2006; 83(3):658-664.

Wei W., et al. The value of TissueLink haemostatic sealer in hepatecomy for hepatocellular carcinoma. Ai Zheng 2006; 25(11):1443-6 (in Chinese).

Aloia TA., et al. Two-surgeon technique for hepatic parenchymal transection of the noncirrhotic liver using saline-linked cautery and ultrasonic dissection. Annals of Surgery 2005; 242(2):172-7.

Ogata S, Kiannmanesh R, Varma D et al. Improvement of surgical margin with a coupled saline radio-frequency device for multiple colorectal liver metastases. JHBP Surgery. 2005; 12(6):498-501.

Buell J, Koffron A, Thomas M et al. Laparoscopic liver resection. J of the American College of Surgeons 2005; 200(3):472-80.

Clayman RV. TissueLink device for laparoscopic nephron-sparing surgery. Journal of Urology 2005; 174(4 pt1):1248-1249.

Di Carlo I, Sofia M, Toro A et al. Colorectal liver metastases resected with safe margin achieved by TissueLink monopolar floating ball. Suppl Tumori 2005; 4(3):S37-8 (in Italian).

Di Carlo I, Toro A, Sofia M et al. Use of the floating ball for hepatic resection in cirrhotic patients affected by hepatocellular carcinoma. G Chir 2005; 26(8-9):321-7 (in Italian).

Fioole B, van der Bilt JD, Elias SG et al. Precoagulation minimizes blood loss during standardized hepatic resection in an experimental model. British Journal of Surgery 2005; 92(11):1409-1416.

Lesurtel M, Selzner M, Petrowsky H et al. How should transection of the liver be performed? A prospective, randomized study in 100 consecutive patients: comparing four different transection strategies. Annals of Surgery 2005; 242(6):814-22.

Poon RT, Fan ST, Wong J. Liver resection using a saline-linked radiofrequency dissecting sealer for transection of the liver. Journal of American College Surgeons 2005; 200(2):308-313.

Herrell SD, Levin BM. Laparoscopic partial nephrectomy: Uue of the TissueLink haemostatic dissection device. Journal of Endourology 2005; 19(4):446-9.

Vanlangendonck R, Venkatesh R, Vulin C et al. Laparoscopic ureterocalicostomy: development of a technique simplified by application of nitinol clips and a wet monopolar electrosurgery device. Journal of Endourology 2005; 19(2):225-9.

Tan YH, Young MD, L’Esperance JO et al. Hand-assisted laparoscopic partial nephrectomy without hilar vascular clamping using a saline-cooled, high-density monopolar radiofrequency device.” Journal of Endourology 2004; 18(9):883-7.

Stern JA, Simon SD, Ferrigni RG et al. TissueLink device for laparoscopic nephron-sparing surgery. Journal of Endourology 2004; 18(5):455-6.

Buell JF, Thomas MJ, Doty TC et al. An initial experience and evolution of laparoscopic hepatic resectional surgery. Surgery 2004; 136(4):804-811.

Di Carlo I, Barbagallo F, Toro A et al. Hepatic resections using a water-cooled, high-density, monopolar device: a new technology for safer surgery. Journal of Gastrointestinal Surgery 2004; 8(5):596-600.

Gruttadauria S, Doria C, Vitale CH et al. Preliminary report on surgical technique in hepatic parenchymal transection for liver tumors in the elderly: a lesson learned from living related liver transplantation. Journal of Surgical Oncology 2004; 88(4):229-233.

Sakamoto Y, Yamamoto J, Kokudo N et al. Bloodless liver resection using the monopolar floating ball plus Ligasure diathermy: preliminary results of 16 liver resections. World Journal of Surgery 2004; 28(2):166-172.

Topp SA, McClurken M, Lipson D et al. Saline-linked surface radiofrequency ablation: factors affecting steam popping and depth of injury in pig liver. Annals of Surgery 2004; 239(4):518-527.

Urena R, Mendez F, Woods M et al. Laparoscopic partial nephrectomy of solid renal masses without hilar clamping using a monopolar radiofrequency device. Journal of Urology 2004; 171(3):1054-6.

Simon SD, Ferrigni RG, Novicki DE et al. Mayo Clinic Scottsdale experience with laparoscopic nephron sparing surgery for renal tumors. Journal of Urology 2003; 169(6):2059-62.

Sundaram CP, Rehman J, Venkatesh R et al. Haemostatic laparoscopic partial nephrectomy assisted by a water-cooled, high-density, monopolar device without renal vascular control. Urology 2003; 61(5):906-9.

Lin E, Gonzalez R, Venkatesh KR et al. Can current technology be integrated to facilitate laparoscopic liver donor hepatectomy? Surgical Endoscopy 2003; 17(5):750-3.

Sims C. Histological characteristics of laparoscopic saline-enhanced electrosurgery of liver and splenic injuries. Surgical Endoscopy 2003; 17(11):1739-43.

Velanovich V, Weaver M. Partial splenectomy using a coupled saline-radiofrequency haemostatic device. American Journal of Surgery 2003; 185(1):66-68.

Strasberg S, et al. "Utility of Saline-Linked RF Ablation in Liver Surgery: Effect of Power, Surface Diameter and Inflow Occlusion on Depth of Liver Destruction in Humans." International Hepato-Pancreato Biliary Association 2006; Edinburgh, Scotland.

Truty MJ, Kendrick ML, Farnell MB, Harold. Management of the Pancreatic Stump in the Modern Era. Pancreas Club 2006; Los Angeles, Ca.

Choti D. The Oncological Effect of the TissueLink device on Liver Surface Tumors and Positive Margins. American Hepato-Pancreato-Biliary Association 2005; Fort Lauderdale, Fl.

Geller D., et al. Results in Liver Surgery. Surgeon Forum 2003; New Orleans, La.

Sturgeon C, Helton WS, Lamba A et al. Early Experience Employing Linear Radiofrequency Pretransection Hepatic Coagulation. American Hepato-Pancreato-Biliary Association 2003; Fort Lauderdale, Fl.