Durepair Dura Regeneration Matrix

What It Is

What Is Durepair Dura Regeneration Matrix?

Cerebrospinal fluid (CSF) leaks during surgery often result in extra time in the operating room. A CSF leak after surgery will require re-operation – adding more time and cost to a patient’s care. In addition, products that are too delicate and difficult to handle are wasteful, time consuming, and frustrating to work with. Durepair^® was manufactured to address these issues.

Durepair is a non-synthetic dura substitute for repair of the dura mater during neurosurgical procedures. It uses a patented technology to produce a strong yet flexible collagen matrix that can be applied as an onlay or suturable graft.

Flexibility

• Can be used as an onlay or suturable graft
• Conforms to the patient’s own dura
• Can be trimmed wet or dry
• Graft will adhere only to the dura – not the brain or fascia

Strength

• Collagen matrix creates a product that is strong yet pliable
• Collagen matrix seals around suture holes to avoid CSF leakage
• Porosity of material is just right for tissue ingrowth

Convenience

• Refrigeration not needed (2°–30° C/35°–86° F)
• Easy to handle and reposition when wet
• Easy to prepare for surgery – hydrates in 30–60 seconds
• Available in a variety of sizes for small leaks and large repairs

How It Works

Durepair^® Dura Regeneration Matrix consists of both Type I and Type III collagen. Durepair is unique in that it uses Type III fetal bovine tissue that has gone through an extensive patented process to remove the cellular components. This leaves undamaged pure collagen that acts as a neutral tissue. The entanglement of strong collagen cables form a highly porous matrix – typically 10–100 micron pores. This matrix is a scaffold for the ingrowth of fibroblasts and blood vessels.