THE RENAL DENERVATION BLOOD PRESSURE PROCEDURE
Designed for treating hypertension
An evidence-based option to help reduce high blood pressure1-3
A non-drug, non-lifestyle option for reducing high blood pressure.
Treatment of high blood pressure, or hypertension, has traditionally been through lifestyle changes, such as diet and exercise, and medications.4
There is also another, complementary approach - a blood pressure procedure called renal denervation (RDN).
Understand high blood pressure.
High blood pressure, a very common health issue around the world, often has no symptoms but raises the risk of heart attacks, strokes, heart failure, and kidney failure.4,5
~46%
of adults with high blood pressure are unaware they have it.4
~80%
of people with high blood pressure do not have it under control.4
> 1 billion
people are affected worldwide.4
The health risks of high blood pressure
Known as the “silent killer”5, high blood pressure often has no symptoms but raises serious health risks4
- Affects men and women of all ages and health backgrounds4
- Raises the risk of heart attacks, strokes, heart failure, and kidney failure4,6
- These risks can be serious—especially if high blood pressure is untreated6
A procedural option for blood pressure control
The renal denervation blood pressure procedure is an evidence-based, minimally invasive procedure that may be indicated for patients with uncontrolled hypertension.7 Designed to be used in conjunction with lifestyle modifications and medications, it has been shown to significantly and sustainably reduce blood pressure.1-3,8 For some patients, it may also allow the number or dosage of blood pressure medications to be reduced.8
A same-day or overnight hospital procedure
The renal denervation blood pressure procedure is a single, minimally invasive procedure that usually takes about an hour and is done in a hospital. Some people go home the same day and others stay overnight and go home the next day. The medical team will decide what is right for each patient.
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References
1
Böhm M, Kario K, Kandzari DE, et al. Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomized, sham-controlled trial. The Lancet 2020: Published online March 29, 2020.
2
Kandzari DE, Böhm M, Mahfoud F, et al. Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial. The Lancet 2018; Jun 9;391(10137): 2346-55.
3
Townsend RR, Mahfoud F, Kandzari DE, et al. Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial. The Lancet 2017; 390: 2160–70.
4
World Health Organisation. Hypertension fact sheet. 2022. Available at https://www.who.int/news-room/fact-sheets/detail/hypertension. (Accessed February 4 2022).
5
American Heart Association. What is High Blood Pressure? https://www.heart.org/en/health-topics/high-blood-pressure/the-facts-about-high-blood-pressure/what-is-high-blood-pressure. Accessed 23 July 2024
6
Whelton P, Carey R, Aranow W, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Originally published 13 Nov 2017 https://doi.org/10.1161/HYP.0000000000000065. . Hypertension 2018; 71: e13-e115.
7
Mancia R, Kreutz R, Brunstrom M, et al. European Society of Hypertension 2023 Guidelines for the management of arterial hypertension. Journal of Hypertension 2023, 41:1874–2071
8
Mahfoud F, Kandzari DE, Kario K, et al. Long-term efficacy and safety of renal denervation in the presence of antihypertensive drugs (SPYRAL HTN-ON MED): a randomised, sham-controlled trial. The Lancet 2022; 399(10234): 1401-10.