Smart insulin products
Smart MDI
<p>The Smart MDI system includes a continuous glucose monitor (CGM), an injection port, and smart insulin pen.</p>
Starting April 25, 2025, Medtronic will be discontinuing the sales of the Guardian™ Connect system, including the sensor and transmitter. The mobile app will no longer be available after October 24, 2025.
For more information, including alternative therapy options, visit the Guardian™ Connect system webpage.

What is Smart MDI?
For people who manage their diabetes with insulin injections, Smart MDI helps relieve the physical and mental effort required, by using an ecosystem of smart-enabled technology devices, to help make your life a bit easier.
If your patient isn’t ready for or interested in a pump, Smart MDI offers some of the advantages of insulin pumps while still offering the freedom of daily injections. The Smart MDI family works together to help your patients stay ahead of their diabetes.
Three powerful tools to help your patients stay ahead of diabetes
Guardian™ Connect system
- 98.5% low detection accuracy1
Accuracy when it matters most - Predictability up to an hour in advance†
Extra time to take action - Automatic uploads
The data you want when you need it — helps avoid wasted appointments
InPen™ smart insulin pen
- Shareable reports
More data = less time waiting - Dose reminders
For those forgotten mealtime shots - Half-unit doses
For those with insulin sensitivity
i-Port Advance™ injection port
- 93% reduction in needle pokes‡
It takes the shots for them - Comfortable and dependable§
Helps with compliance - Auto-insertion device included
For those with fear of pokes
Real-time blood glucose readings, trends, and alerts
❶ Helps prevent highs, alerting if trending high
❷ Helps prevent lows, alerting if at low, or trending low
† Alerts must be set to receive predictive alerts.
‡ Based on 150 injections per month versus 10 insertions per month.
§ Survey data on file; individual results may vary.
1. Guardian™ Connect system SSED, page 19, Table 5. 98.5% Glucose Correct Detection Rate based on Predictive Alerts at 30 minutes when worn on the abdomen.