Micra™ AV

AccelAV primary study results

The first prospective multicenter study of Micra AV concludes that it significantly improves quality of life in patients with AV block and normal sinus function.1

Study objective

To report on the performance of the Micra AV leadless ventricular pacemaker with accelerometer-based algorithms that provide AV synchronous pacing.

Study design

  • Prospective, single-arm, multicenter, global study
  • 152 subjects
  • 20 centers in the United States and Hong Kong
  • Patients implanted with a Micra AV
    • N = 54 with complete AV block and normal sinus function (primary analysis cohort)
    • N = 20 with complete AV block, normal sinus function, and optimized programming (optimized sub-study cohort)


Improvement from optimized programming is most pronounced at elevated rates.

Sustained resting AV synchrony
85.4% and stable through three months.

Improved ambulatory AV synchrony
82.6% with optimized programming.

No upgrades through three months
No major complications due to pacemaker syndrome.

Ambulatory AV synchronous pacing by sinus rate during a 24-hour period

Graph of Micra AccelAV study showing ambulatory AV synchronous pacing by sinus rate during a 24-hour period

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Educational resources on Medtronic Academy

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Chinitz LA, El-Chami MF, Sagi V, et al. Ambulatory AV synchronous pacing over time using a leadless ventricular pacemaker: Primary results from the AccelAV study. Heart Rhythm. September 6, 2022:S1547-5271(22)02380-3.