Infusion Sets Product Support

Comparing Infusion Sets


Changing your Infusion Set

Medtronic Extended infusion set


Watch these how-to videos for instructions on inserting a MiniMed Quick-Set infusion set 

MiniMedTM Quick-setTM Infusion Set

MiniMedTM Sure-TTM Infusion Set

MiniMedTM MioTM Infusion Set

MiniMedTM MioTM Advance Infusion Set

MiniMedTM SilhouetteTM Infusion Set

MiniMedTM MioTM 30


It is important to prevent insulin from accidently getting on top of the reservoir, which could transfer liquid onto the infusion set membrane in the tubing connector. If insulin or any liquid gets inside the tubing connector, it can temporarily block the vents that allow the pump to properly deliver insulin. This may result in the delivery of too little or too much insulin, which could cause hyperglycemia or hypoglycemia.

To help prevent this from occurring, keep these 3 important steps in mind when changing your set:

  1. Always keep the vial upright when removing the reservoir from the tubing connector.

  2. If insulin or any other liquid has gotten on the top of the reservoir or inside the tubing connector, discard both and start over with a new reservoir and infusion set.

  3. If insulin continues to drip or squirt from the infusion set cannula after priming/fill tubing has been completed, do not insert. Start over with a new reservoir and infusion set.

Infusion Site and insertion sites

Best body areas for infusion set insertion

Infusion set or tubing issue? 

  • Disconnect at your site and purge the air bubbles from the tubing using the fill cannula or prime feature.
  • Call 24-Hour HelpLine at 1-800-284-4416, option 1 and 1

Troubleshooting High Blood Glucose After Set Change

If you experience a high blood glucose (BG) that does not come down with a correction bolus, follow the tips here. These tips will help you determine if an issue exists with your infusion site, infusion set, pump or your insulin. If you determine your infusion site, infusion set, pump and insulin are OK, continue to follow the protocol for treating a high BG and contact your healthcare professional.


Things to Examine Questions to Ask Solutions

Infusion site problem?


Reservoir issue?



Tubing issue?

Is it red, irritated, or painful?


Is the reservoir empty?

Are there excessive bubbles?


Is there blood in the tubing?

If yes, change the infusion site, infusion set, reservoir with insulin
Reservoir and infusion set connection issue? Are there leaks or breaks? If yes, attempt to tighten the connection. If problem persists, change theinfusion site, infusion set, and reservoir with insulin.
Is connection loose or easily moved?
Infusion set or tubing issue? Are there bubbles, larger than champagne bubbles, in the tubing? If yes, use your at site disconnect and then purge air bubbles from the tubing using the fill cannula or prime feature

Pump Settings issue?

  • Bolus Delivery
  • Basal Rates
  • Time
Was last meal bolus missed? If yes, give correction dose
Are basal rates and times set correctly? If not,set basal rates correctly
Is time (AM/PM) set correctly? If not, set time correctly
Denatured or “bad” insulin? Has insulin vial expired or been exposed to high temperatures or direct sunlight? If yes, replace with a new vial of insulin and change your infusion set and reservoir with insulin
Has your pump and reservoir been exposed to high temperatures or direct sunlight?
Insulin pump problem? Is pump inoperable? Call the 24-Technical Support at number 1-800-284-4416.
Not sure if pump has a problem?

Information on this site should not be used as a substitute for talking with your doctor. Always talk with your doctor about diagnosis and treatment information.