Patient-Ventilator Asynchrony Incidence

Greater than 10% of total breaths

The incidence of patient-ventilator asynchrony is influenced by the definition of asynchrony, patient condition, ventilator mode, and method of observation.

INCIDENCE OF ASYNCRONY BY CONDITION AND MODE MEASURED IN PERCENTAGE OF PATIENTS WITH ASYNCHRONY IN GREATER THAN 10% OF TOTAL BREATHS
CITATION NUMBER OF PARTICIPANTS CONDITION MODE % OF PATIENTS WITH ASYNCHRONY INDEX* > 10
BLANCH 2015([FOOTNOTE=Blanch L, Villagra A, Sales B, et al. Asynchronies during mechanical ventilation are associated with mortality. Intensive care medicine. 2015;41(4):633-641.],[ANCHOR=View Abstract],[LINK=/content/mitg/websites/languagemasters/emea/en-gb/support/clinical-evidence.html?id=906058]) 50 ICU Invasive Ventilation > 24 hrs PCV, PSV, VCV 12
CARLUCCI 2013([FOOTNOTE=Carlucci A, Pisani L, Ceriana P, Malovini A, Nava S. Patient-ventilator asynchronies: may the respiratory mechanics play a role? Critical care (London, England). 2013;17(2):R54.],[ANCHOR=View Abstract],[LINK=/content/mitg/websites/languagemasters/emea/en-gb/support/clinical-evidence.html?id=956126]) 69 ICU Invasive Ventilation > 24 hrs NIV, PSV 30
ROBINSON 2013([FOOTNOTE=Robinson BR, Blakeman TC, Toth P, Hanseman DJ, Mueller E, Branson RD. Patient-ventilator asynchrony in a traumatically injured population. Respiratory care. 2013;58(11):1847-1855. ],[ANCHOR=View Abstract],[LINK=/content/mitg/websites/languagemasters/emea/en-gb/support/clinical-evidence.html?id=1203233]) 35 Trauma SIMV, PSV 25.7
VIGNAUX 2009([FOOTNOTE=Vignaux L, Vargas F, Roeseler J, et al. Patient-ventilator asynchrony during non-invasive ventilation for acute respiratory failure: a multicenter study. Intensive care medicine. 2009;35(5):840-846.],[ANCHOR=View Abstract],[LINK=/content/mitg/websites/languagemasters/emea/en-gb/support/clinical-evidence.html?id=603142]) 60 Acute respiratory failure (acute chronic respiratory failure, pneumonia, post-extubation, pulmonary edema, postoperative, thoracic trauma) NIV mode - ICU Ventilator 43
VIGNAUX 2010([FOOTNOTE=Vignaux L, Tassaux D, Carteaux G, et al. Performance of noninvasive ventilation algorithms on ICU ventilators during pressure support: a clinical study. Intensive care medicine. 2010;36(12):2053-2059.],[ANCHOR=View Abstract],[LINK=/content/mitg/websites/languagemasters/emea/en-gb/support/clinical-evidence.html?id=1203239]) 65 Acute respiratory failure (acute episode of chronic pulmonary disease, NIV after extubation, pneumonia, post-operative, pulmonary edema) NIV mode - ICU Ventilator 38
THILLE 2006([FOOTNOTE=Thille AW, Rodriguez P, Cabello B, Lellouche F, Brochard L. Patient-ventilator asynchrony during assisted mechanical ventilation. Intensive care medicine. 2006;32(10):1515-1522.],[ANCHOR=View Abstract],[LINK=/content/mitg/websites/languagemasters/emea/en-gb/support/clinical-evidence.html?id=805246]) 62 ICU Invasive Ventilation > 24 hrs ACV, PSV 24

*Asynchrony Index (expressed in percentage) = number of asynchrony events/total respiratory rate (ventilator cycles +wasted efforts)×100

ACRONYMS
ACV Assist-control Ventilation
NIV Non-invasive Ventilation
PCV Pressure-control Ventilation
PSV Pressure-support Ventilation
VCV Volume-control Ventilation

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