Gain insight into brain response with BIS™ technology([FOOTNOTE=Dershwitz M. Should we measure depth of anesthesia? Seminars in Anesthesia, Perioperative Medicine and Pain. 2001;20(4):246-256.],[ANCHOR=],[LINK=])

Bispectral Index™ (BIS™) monitoring enhances the clinician’s patient-­targeted approach to induction, maintenance and emergence. BIS™ technology noninvasively measures and interprets brain wave activity directly related to the effects of anesthetic agents.

Among other benefits, BIS™ technology:

  • Helps the clinician customize anesthetic dosing to individual patient physiologies
  • Indicates hypnotic effect through the easy-­to-­read BIS™ index
  • Facilitates improved patient outcomes as validated in multiple clinical studies([FOOTNOTE=Gan TJ, Glass PS, Windsor A, et al. Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil, and nitrous oxide anesthesia. BIS Utility Study Group. Anesthesiology. 1997;87(4):808-815.],[ANCHOR=],[LINK=]),([FOOTNOTE=Punjasawadwong Y, Boonjeungmonkol N, Phongchiewboon A. Bispectral index for improving anaesthetic delivery and postoperative recovery. Cochrane Database of Systematic Reviews. 2007;17(4):CD003843.],[ANCHOR=],[LINK=]),([FOOTNOTE=White PF, Ma H, Tang J, Wender RH, Sloninsky A, Kariger R. Does the use of electroencephalographic bispectral index or auditory evoked potential index monitoring facilitate recovery after desflurane anesthesia in the ambulatory setting? Anesthesiology. 2004;100(4):811-817.],[ANCHOR=],[LINK=]),([FOOTNOTE=Myles PS, Leslie K, McNeil J, Forbes A, Chan MT. Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial. Lancet. 2004;363(9423):1757-1763.],[ANCHOR=],[LINK=]),([FOOTNOTE=Avidan MS, Zhang L, Burnside BA, et al. Anesthesia awareness and the bispectral index. N Engl J Med. 2008;13;358(11):1097-1108.],[ANCHOR=],[LINK=]),([FOOTNOTE=Avidan MS, Mashour GA. Prevention of intraoperative awareness with explicit recall: making sense of the evidence. Anesthesiology. 2013;118(2):449-456.],[ANCHOR=],[LINK=]),([FOOTNOTE=Ekman A, Lindholm ML, Lennmarken C, Sandin R. Reduction in the incidence of awareness using BIS monitoring. Acta Anaesthesiol Scand. 2004;48(1):20-26.],[ANCHOR=],[LINK=]),([FOOTNOTE=Luginbühl M, Wüthrich S, Petersen-Felix S, Zbinden AM, Schnider TW. Different benefit of bispectal index (BIS) in desflurane and propofol anesthesia. Acta Anaesthesiol Scand. 2003;47(2):165-173.],[ANCHOR=],[LINK=])

BIS™ TIVA Outcomes

Discover how BIS™-based protocols can help you confidently monitor and tailor safe, optimal anesthesia for each patient.

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  • The monitor translates the raw EEG data into the easy-­to-­read BIS™ index.
  • The monitor provides a user-­configurable display.
  • The monitor is a versatile platform designed for future expandability.
Order Information
Order Code Description Unit of Measure Quantity
186-0210 BIS™ Complete 2-Channel Monitor Each 1
Parameters BIS, SQI, EMG, SR, BC, EEG
Trended parameters BIS, SQI, EMG, SR, BC
BIS™ alarm Upper and lower limit, results in visual and audible alert when out of range

Order Information


BIS™ technology offers clinicians added security for providing specialized care and comfort for patients, including those who may be more sensitive to the hemodynamic effects of anesthesia.

BIS™ monitoring technology provides valuable information about patient status to help clinicians address each patient’s unique anesthetic requirements. This may be particularly valuable for:

  • Patients with complex conditions whose status may suddenly or frequently change
  • Patients with cardiovascular conditions
  • Obese patients
  • Trauma patients or others requiring reduced levels of anesthesia
  • BIS™ monitoring technology enable clinicians to manage anesthetic goals of hypnosis, analgesia and immobility.
  • BIS™ monitoring technology enables clinicians to assess consciousness and sedation separately from cardiovascular reactivity.
  • BIS™ technology may help:
    • Reduce emergence and recovery time2
    • Reduce anesthetic drug use2
    • Reduce the risk of awareness during surgery5,8