Gain insight into brain response with BIS™ technology([FOOTNOTE=Dershwitz M. Should we measure depth of anesthesia? Seminars in Anesthesia, Perioperative Medicine and Pain. 2001; 20(4) : 246-256.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=804982])

Bispectral Index™ (BIS™) monitoring enhances the clinician’s patient-targeted approach to induction, maintenance and emergence. BIS™ technology non-­invasively measures and interprets brain wave activity directly related to the effects of anesthetic agents:

  • Helps the clinician customize anesthetic dosing to individual patient physiologies
  • Indicates hypnotic effect through the easy-­to-­read BIS™ index
  • Facilitates improved patient outcomes as validated in multiple clinical studies([FOOTNOTE=Gan TJ, Glass PS, Windsor A, et al. Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil, and nitrous oxide anesthesia. BIS™ Utility Study Group. Anesthesiology. 1997; 87(4): 808-815.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35754]),([FOOTNOTE=Punjasawadwong Y, Boonjeungmonkol N, Phongchiewboon A. Bispectral index for improving anaesthetic delivery and postoperative recovery. Cochrane Database of Systematic Reviews. 2007; 17(4): CD003843.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=185841]),([FOOTNOTE=White PF, Ma H, Tang J, Wender RH, Sloninsky A, Kariger R. Does the use of electroencephalographic bispectral index or auditory evoked potential index monitoring facilitate recovery after desflurane anesthesia in the ambulatory setting? Anesthesiology. 2004;100(4): 811-817.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35731]),([FOOTNOTE=Myles PS, Leslie K, McNeil J, Forbes A, Chan MT. Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial. Lancet. 2004 ; 363(9423) : 1757-1763.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35729]),([FOOTNOTE=Avidan MS, Zhang L, Burnside BA, et al. Anesthesia awareness and the bispectral index. N Engl J Med. 2008;13;358(11) : 1097-1108.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=185918]),([FOOTNOTE=Avidan MS, Mashour GA. Prevention of intraoperative awareness with explicit recall: making sense of the evidence. Anesthesiology. 2013; 118(2): 449 - 456.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=301466]),([FOOTNOTE=Ekman A, Lindholm ML, Lennmarken C, Sandin R. Reduction in the incidence of awareness using BIS™ monitoring. Acta Anaesthesiol Scand. 2004; 48(1): 20-26.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=117525]),([FOOTNOTE=Luginbühl M, Wüthrich S, Petersen-Felix S, Zbinden AM, Schnider TW. Different benefit of bispectal index (BIS™) in desflurane and propofol anesthesia. Acta Anaesthesiol Scand. 2003; 47(2): 165-173.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=35736])

BIS™ TIVA Outcomes

Discover how BIS™-based protocols can help you confidently monitor and tailor safe, optimal anesthesia for each patient.

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The BIS™ Complete 4-­channel monitor translates the raw EEG data into the easy-­to-­read BIS™ index.

The monitor provides:

  • User-­configurable display
  • Versatile platform for future expandability
  • Four-­channel EEG monitoring
  • Asymmetry Indicator (ASYM)
  • Ability to trend BIS-­Left and BIS-­Right values
Order Information
Order Code Description Unit of Measure Quantity
186-1014 BIS™ Complete 4-Channel Monitoring System Each 1
186-0224-AMS BIS™ LOC 4-Channel Monitor with Patient Interface Cable (PIC-4) Each 1
186-0212 BIS™ Bilateral Sensor Each 1
Parameters BIS, SQI, EMG, SR, BC, TP, SEF, EEG
Trended parameters BIS, SQI, EMG, SR, BC, SEF
BIS™ alarm upper and lower limit, results in visual and audible alert when out of range

Order Information


BIS™ technology offers the clinician added security for providing specialized care and comfort for their patients, including those who may be more sensitive to the hemodynamic effects of anesthesia.

BIS™ monitoring provides invaluable information about patient status to help clinicians address their unique anesthetic requirements. This may be particularly valuable for:

  • Patients with complex conditions whose status may suddenly or frequently change
  • Patients with cardiovascular conditions
  • Obese patients
  • Trauma patients or others requiring reduced levels of anesthesia
  • BIS™ monitoring technology enables clinicians to manage anesthetic goals of hypnosis, analgesia and immobility.
  • BIS™ monitoring technology enables clinicians to assess consciousness and sedation separately from cardiovascular reactivity.
  • Reduce emergence and recovery time2
  • Reduce anesthetic drug use2
  • Reduce the risk of awareness during surgery5,8