Monitoring with BIS™ technology empowers you with an accurate, direct measurement of the propofol effect on your patient’s brain.
In order to personalize your propofol dosing based on the individual needs of each patient, you need a direct measurement of the propofol effect on your patient’s brain. BIS™ monitoring empowers you by accurately reflecting the anesthetic effect on your patient’s brain, allowing you to personalize dosing to:
“Bispectral index (BIS)-guided anaesthesia may also reduce early recovery parameters of the time to eye opening, the time to orientation, and the time to discharge from the postanaesthesia care unit (PACU).”1
– Authors Sharon Lewis, et al., in a clinical review of bispectral index for improving anesthetic deliver and postoperative recovery in adults.
“BIS™ monitoring is recommended as an option for all patients receiving total intravenous anesthetic (TIVA). BIS™ technology is also cost effective in this patient population due to the inability to measure end-tidal anesthetic concentration.”12
– National Institute for Health and Clinical Excellence
“…in intravenous anesthesia, BIS™ monitoring could reduce the incidence of intraoperative awareness by approximately 80% (0.1448% versus 0.7330%).”9
– Author Wen-Wei Gao, et al., in a clinical review on BIS™ monitoring on interoperative awareness
The BIS™ monitoring system should not be used as the sole basis for diagnosis or therapy and is intended only as an adjunct in patient assessment. Reliance on the BIS™ monitoring system alone for intraoperative anesthetic management is not recommended.
1. Lewis SR, Pritchard MW, Fawcett LJ, Punjasawadwong Y. Bispectral index for improving intraoperative awareness and early postoperative recovery in adults. Cochrane Database Syst Rev. 2019;9:CD003843. doi:10.1002/14651858.CD003843.pub4.
2. Zhang C, Xu L, Ma Y-Q, et al. Bispectral index monitoring prevent awareness during total intravenous anesthesia: a prospective, randomized, double-blinded, multi-center controlled trial. Chin Med J (Engl). 2011;124(22):3664-3669
3. Myles PS, Leslie K, McNeil J, Forbes A, Chan MTV. Bispectral index monitoring to prevent awareness during anaesthesia: The B-Aware randomised controlled trial. Lancet. 2004;363(9423):1757-1763. doi:10.1016/S0140-6736(04)16300-9.
4. Ekman A, Lindholm M-L, Lennmarken C, Sandin R. Reduction in the incidence of awareness using BIS monitoring. Acta Anaesthesiol Scand. 2004;48(1):20-26. doi:10.1111/j.1399-6576.2004.00260.x.
5. Punjasawadwong Y, Phongchiewboon A, Bunchungmongkol N. Bispectral index for improving anaesthetic delivery and postoperative recovery. Cochrane Database Syst Rev. 2014;(6):CD003843. doi:10.1002/14651858.CD003843.pub3.
6. Song D, Joshi GP, White PF. Titration of volatile anesthetics using bispectral index facilitates recovery after ambulatory anesthesia. Anesthesiology. 1997;87(4):842-848.
7. Gan TJ, Glass PS, Windsor A, et al. Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil and nitrous oxide anesthesia. Anesthesiology. 1997;87(4):808-815. doi:10.1097/00000542-199710000-00014
8. Luginbuhl M, Wuthrich S, Petersen-Felix S, Zbinden AM, Schnider TW. Different benefit of bispectal index (BIS) in desflurane and propofol anesthesia. Acta Anaesthesiol Scand. 2003;47(2):165-173.
9. Gao WW, He YH, Liu L, Yuan Q, Wang YF, Zhao B. BIS monitoring on intraoperative awareness: a meta-analysis. Current medical science. 2018;38(2):349-53.
10. Chiu CL, Ong G, Majid AA. Impact of bispectral index monitoring on propofol administration in patients undergoing cardiopulmonary bypass. Anaesthesia Intensive Care. 2007;35:342-347.
11. Lau CSM, Chamberlain RS. Enhanced recovery after surgery programs improve patient outcomes and recovery: A meta-analysis. World J Surg. 2017;41: 899–913. doi: 10.1007/s00268-016-3807-4.
12. National Institute for Health and Clinical Excellence. Depth of anaesthesia monitors (E-Entropy, BIS™ and Narcotrend) (DG6). November 2012.