The Puritan Bennett™ Bi-Level software option provides two strategies for enabling patients to breathe spontaneously at both upper and lower positive airway pressure levels, helping to improve synchrony.
The Bi-Level software option has been shown to be associated with a reduction of opioid use by 40% in critically ill cancer patients under mechanical ventilator support.([FOOTNOTE=Saul J et al. The effect of Bi-Level ventilation on opioid utilization in a medical intensive care unit. Resp Care. 2000;45(8):1013.],[ANCHOR=],[LINK=])
The Puritan Bennett™ Bi-Level software mode offers distinct enhancements over pressure support and pressure control, particularly in spontaneously breathing patients:
Additionally, Bi-Level mode offers expanded Pressure Support (PS) capabilities. When the time at lower PEEP is set long enough to allow spontaneous breathing, PS can be used. If the PS level is set high enough, the breaths at the upper PEEP can also be pressure-supported.
The clinical advantages of spontaneous breathing at two PEEP levels include:
A decrease in sedation
If the patient is allowed to breathe spontaneously during all phases of support, and transition between pressure levels is synchronized, sedation due to patient/ventilator dyssynchrony may be kept at a lower level.([FOOTNOTE=Lefebvre DL, Stock C. Airway pressure release ventilation. The Department of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia.],[ANCHOR=],[LINK=]),([FOOTNOTE=Müller E. Clinical application of novel ventilation techniques. Int J Artif Organs. 1995;18(10):656-669.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=882301]),([FOOTNOTE=Burchardi H, Rathgeber J, Sydow M. The concept of analgo-sedation depends on the concept of mechanical ventilation.Yearbook of Intensive Care and Emergency Medicine. 1995. Berlin.],[ANCHOR=],[LINK=]),([FOOTNOTE=Sydow M, Burchardi H, Ephraim E, Zielmann S, Crozier TA. Long-term effects of two different ventilatory modes on oxygenation in acute lung injury. Comparison of airway pressure release ventilation and volume-controlled inverse ratio ventilation. Am J Respir Crit Care Med. 1994;149(6):1550-1556.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=882299]),([FOOTNOTE=Stock MC. Conceptual basis for inverse ratio and airway pressure release ventilation. Seminars in Respiratory Medicine. July 1993;14(4):270-274.],[ANCHOR=],[LINK=])
Improved patient monitoring
Bi-Level mode provides enhanced monitoring information that can assist with clinical decisions. It monitors mandatory and spontaneous tidal volumes and minute volume separately, which offers the clinician a clear understanding of how the patient’s spontaneous ventilation contributes to total ventilation.
Simplicity and ease of use
Bi-Level software combines two strategies in one mode. By allowing the principles of APRV to easily transition from controlled ventilation to all levels of augmented ventilation, Bi-Level mode may be an appropriate tool for clinicians to manage a patient for the entire course of a patient’s disease process.([FOOTNOTE=Hörmann C, Baum M, Putensen C, Mutz NJ, Benzer H. Biphasic positive airway pressure (BIPAP)--a new mode of ventilatory support. Eur J Anaesthesiol. 1994;11(1):37-42.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=882302]),([FOOTNOTE=Müller E. Clinical application of novel ventilation techniques. Int J Artif Organs. 1995;18(10):656-669.],[ANCHOR=View Abstract],[LINK=/content/covidien/websites/medtronic/com/en/covidien/support/clinical-evidence.html?id=882301])
*Lefebvre DL, Stock C. Airway pressure release ventilation. The Department of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia.