Across the range of products and procedures, LigaSure™ technology delivers a unique combination of pressure and energy to create a consistent seal with each application.

• Provides a combination of pressure and energy to create vessel fusion
• Permanently fuses vessels up to and including 7 mm in diameter and tissue bundles without dissection or isolation
• Average seal cycle is 2 to 4 seconds, when used with the ForceTriad™ energy platform
• Seals withstand three times normal systolic blood pressure
• Feedback-controlled response system automatically discontinues energy delivery when the seal cycle is complete, eliminating the guesswork

LigaSure™ instruments have been found to:

• Have the highest burst pressure, fastest sealing time and were highest rated overall compared to Gyrus PK™^*, Harmonic ACE™^* and ENSEAL™^{*([FOOTNOTE=Lamberton GR, Hsi RS, Jin DH, Lindler TU, JellisonFC, Baldwin DD. Prospective comparison of four laparoscopic vessel ligation devices. J Endourol. 2008;22(10):2307-2312.],[ANCHOR=1],[LINK=])}
• Reduce blood loss compared to sutures and clips ([FOOTNOTE=Ding Z, Wable G, Rane A. Use of LigaSure bipolar diathermy system in vaginal hysterectomy. J Obstet Gynaecol. 2005;25(1): 49-51],[ANCHOR=2],[LINK=])^, ([FOOTNOTE=Levy B, Emery L. Randomized trial of suture versus electrosurgical bipolar vessel sealing in vaginal hysterectomy. Obstet Gynecol. 2003;102(1):147-151],[ANCHOR=3],[LINK=])
• Reduce procedure time compared to sutures ^2,3
• Reduce patient length of stay compared to sutures ²

Compared to mechanical ligation techniques, LigaSure™ technology has been shown to:

• Significantly reduce operative blood loss in colorectal, gynecologic and urologic surgery ([FOOTNOTE=Targarona, et al. A prospective randomized comparison of conventional electrosurgery, biopolar computer-controlled electrosurgery and ultrasonic dissection. Operative Outcome and Cost analysis. Surgical Innovation. 2005 Dec;12(4):339-344],[ANCHOR=],[LINK=])^,([FOOTNOTE=Manouras, et al. Sutureless open low anterior resection with total mesorectal excision for rectal cancer with the use of the electrothermal bipolar vessel sealing system. 2007. Med Sci Monit; 13(5): CR224-230.],[ANCHOR=],[LINK=])^,([FOOTNOTE=Ding Z, et al. Use of LigaSure bipolar diathermy system in vaginal hysterectomy. Journal of Obstetrics Gynaecology. 2005 Jan;25(1):49-51.],[ANCHOR=],[LINK=])^,([FOOTNOTE=Levy B, Emery L. Randomized Trial of Suture Versus Electrosurgical Bipolar Vessel Sealing in Vaginal Hysterectomy. Obstetrics and Gynecology. 2003 Jul;102(1):147-151.],[ANCHOR=],[LINK=])^,([FOOTNOTE=Tamussino K, et al. Electrosurgical bipolar vessel sealing for radical abdominal hysterectomy. Gynecologic Oncology. 2005 Feb; 96(2):320-322.],[ANCHOR=],[LINK=])^,([FOOTNOTE=Leonardo C, et al. Laparoscopic nephrectomy using LigaSure system: preliminary experience. Journal of Endourology. 2005 Oct;19(8):976-8.],[ANCHOR=],[LINK=])
• Significantly reduce perioperative blood transfusions in gynecologic, urologic and general surgery ^8, ([FOOTNOTE=Daskalopoulos G et al. Electrothermal bipolar coagulation for radical prostatectomies and cystectomies: a preliminary case-controlled study. International Urology and Nephrology. 2004;36(2):181-185.],[ANCHOR=],[LINK=])^, ([FOOTNOTE=Romano F, et al. Laparoscopic Splenectomy: LigaSure versus EndoGIA: A Comparative Study. J Laparoendoscopic & Adv Surg Techniques. 2007. Vol. 17, No. 6.],[ANCHOR=],[LINK=])
• Significantly reduce procedure time in colorectal, gynecologic and urologic surgery ^{4, 6, 7, 9,} ([FOOTNOTE=Cronje HS, et al. Electrosurgical bipolar vessel sealing during vaginal hysterectomy. Int J Gynaecol Obstet. 2005 Dec;91(3):243-5.],[ANCHOR=],[LINK=])^, ([FOOTNOTE=Metzelder ML, et al. Laparoscopic nephroureterectomy in children: a prospective study on LigaSure versus Clip/Ligation. Eur J Pediatr Surg. 2006 Aug;16(4):241-4.],[ANCHOR=],[LINK=])
• Significantly reduce length of hospital stay in gynecologic and urologic surgery ^{6, 13}

Compared to other energy-based modalities, LigaSure™ technology has been shown to:

• Significantly reduce operative blood loss in colorectal and gynecologic surgery ([FOOTNOTE=Araki Y, et al. Clipless hand-assisted laparoscopic total colectomy using LigaSure Atlas. Kurume Medical Journal. 2004;51(2):105-8.],[ANCHOR=],[LINK=])^,([FOOTNOTE=Campagnacci R, et al. Electrothermal bipolar vessel sealing device vs. ultrasonic coagulating shears in laparoscopic colectomies: a comparative study. Surg Endosc. 2007 Feb 8.],[ANCHOR=],[LINK=])^,([FOOTNOTE=Takada et al. Comparative study of electrothermal bipolar vessel sealer and ultrasonic coagulating shears in laparoscopic colectomy. Surgical Endoscopy. 2005;19:226-228.],[ANCHOR=],[LINK=])^,([FOOTNOTE=Demirturk F, et al. Comparison of the use of electrothermal bipolar vessel sealer with harmonic scalpel in total laparoscopic hysterectomy. J Obst Gynaecol Res. 2007; 33 (3):341-345.],[ANCHOR=],[LINK=])
• Significantly reduce procedure time in colorectal and gynecologic surgery ^{14, 17}

What is TissueFect™ sensing technology?

TissueFect™ sensing technology is the control system for the ForceTriad™ energy platform, designed to precisely manage energy delivery, creating a range of options for desired tissue effect. TissueFect™ sensing technology monitors changes in tissue impedance 3,333 times a second, and adjusts energy output accordingly to deliver the appropriate amount of energy for the desired tissue effect.

What is LigaSure™ tissue fusion?

LigaSure™ vessel sealing technology has been updated and improved in the ForceTriad™ energy platform, controlled by TissueFect™ sensing technology. LigaSure™ tissue fusion, like LigaSure™ vessel sealing, uses the body’s own collagen and elastin to create a permanent fusion zone. This technology can fuse vessels up to and including 7 mm, lymphatics, tissue bundles and pulmonary vasculature, and has an average seal cycle of two to four seconds in most surgical situations.