If the chemical composition, coating and braid construction of Polysorb™ suture and the competitor's braided synthetic absorbable suture are essentially the same how is it that Polysorb™ sutures are appreciably stronger?
The sheath and core of Polysorb™ suture utilize a manufacturing process that produces more finer, stronger filaments and provides Polysorb™ with superior tensile strength.
Polysorb™ suture's tensile strength is listed at 80% at 2 weeks and 30% at 3 weeks. The tensile strength of our competitors' braided suture is listed at 75% at 2 weeks, 50% at 3 weeks and 25% at 4 weeks. How can you claim that Polysorb™ is stronger?
Syneture's tensile strength for Polysorb™ is based on a percentage of the USP standard for knot pull strength. It is an industry measurement standard and measures the actual strength of the suture both out-of-package and over time. The competitor's tensile strength claim for their product is not based on the actual strength of the suture over time but instead on the percentage of it's own original strength. If the competitive product lists it's strength at 75% at 2 weeks that means it has 75% of its original strength. In its registration the competition does not use any industry standard as a base point for measurement. In an "apples to apples" test of tensile strength measuring how many kilograms of force it takes to break a suture line, Polysorb™ is appreciably stronger out-of-package and during the critical wound healing period.
I used Polysorb™ sutures before and the knots slipped and the suture unraveled. Why should I try it again?
There have been several improvements made to Polysorb™ in the past few years. The original core-to-sheath ratio was 80% core to 20% sheath. This made the suture more supple but the suture was prone to slipping and separating from the core. The current core-to-sheath ratio is 20% core to 80% sheath. This ratio is equivalent to the competitor's braided synthetic abrsorbable suture. Polysorb™ suture's braid construction and coating were improved to provide better flow through tissue and a more secure knot. When tied down with proper technique, Polysorb™ has a stronger, more secure knot.
Does Polysorb™ have greater tissue reactivity than the competitor's braided synthetic absorbable suture?
Polysorb™ is made up of essentially the same chemical composition as the competitor's product. They are both absorbed by hydrolysis and their absorption profiles are both between 56-70 days. In-vivo testing has shown no measurable difference in reactivity between Polysorb™ and the competitor's braided synthetic absorbable suture.
What is the corresponding suture in the Ethicon portfolio?