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How It Works

  

SYMPLICITY™ BLOOD PRESSURE PROCEDURE

How it works

The Medtronic Symplicity blood pressure procedure provides another management option for people with uncontrolled high blood pressure.*1–3

  

Illustration of a patient receiving blood pressure check with readings of systolic and diastolic blood pressure shown

  

What the Symplicity procedure does

The Symplicity blood pressure procedure calms excessively active nerves connected to the kidneys that may be contributing to your high blood pressure.4

Get more details (opens new window)

Expect a safe and effective procedure.

  • No negative effect on kidney function*3,5-7
  • > 20,000 people worldwide have received it†7

 

One day to help manage your blood pressure

The Symplicity blood pressure procedure usually only takes up one day of your schedule, and can be done on an outpatient basis with your doctor's approval.

Learn more

Listen to real patients.

See how the Symplicity blood pressure procedure has helped people manage their blood pressure.

Testimonials are individual experiences. Their thoughts and opinions are their own. Not every person will experience the same results.

Hear their stories
*

Includes Symplicity Spyral™ and Flex catheters.

†

Through three years in a patient registry.

References

1

Kandzari DE, Böhm M, Mahfoud F, et al. Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial. Lancet. June 9, 2018;391(10137):2346–2355.

2

Böhm M, Kario K, Kandzari DE, et al. Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial. Lancet. May 2, 2020;395(10234):1444–1451.

3

Mahfoud F, Mancia G, Schmieder R, et al. Blood pressure and MACE reductions after renal denervation: 3-year Global Symplicity Registry results. Presented at PCR e-course 2022.

4

Ettehad D, Emdin CA, Kiran A, et al. Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis. Lancet. March 5, 2016;387(10022):957–967.

5

Mahfoud F, Mancia G, Schmieder R, et al. Renal denervation in high-risk patients with hypertension. J Am Coll Cardiol. June 16, 2020;75(23):2879–2888.

6

Böhm M, Mahfoud F, Williams B, et al. Renal denervation with Symplicity Spyral™ catheter in the Global Symplicity Registry: Safety and efficacy at 3 years. Poster. TCT 2019.

7

Medtronic data on file.

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