Sinus implants
<p>The PROPEL™ sinus implant maintains patency and locally delivers steroid to the sinus mucosa in patients 18 years and older following sinus surgery.</p>
PROPEL™ sinus implants keep the sinuses open while releasing mometasone furoate (MF).
PROPEL™ sinus implants feature an innovative two-in-one mechanism that opens in the sinuses while delivering MF, a potent corticosteroid, directly where it is needed.2–4
| Topical corticosteroid | Lipophilicity‡,6 | Potency (receptor affinity)†,7 | Systemic bioavailablity‡,8 |
|---|---|---|---|
| Dexamethasone | Very low (less than 1.0) | Very low (100) | High (76%) |
| Triamcinolone (Kenalog) | Low (1.0) | Low (233) | Medium (46%) |
| Budesonide | Low (1.6) | Intermediate (935) | Medium (34%) |
| Mometasone furoate | High (20.0) | High (2,300) | Very low (less than 1%) |
† Lipophilicity numbers normalized relative to triamcinolone acetonide.
‡ As measured by relative receptor binding affinity compared to dexamethasone, which is set to a value of 100. Higher values designate greater potency.
Readily absorbs into tissue
High glucocorticoid receptor affinity
Minimize systemic effects
| CFN | Product Name | Quantity |
|---|---|---|
| 50011- | PROPEL™ Contour sinus implant | 1 |
| 50011-5 | PROPEL™ Contour sinus implant pack | 5 |
| 60011 | PROPEL™ Mini sinus implant | 1 |
| 600115 | PROPEL™ Mini sinus implant pack | 5 |
| 60044- | PROPEL™ Mini sinus implant with straight delivery system (SDS) | 1 |
| 60044-5 | PROPEL™ Mini sinus implant with straight delivery system (SDS) pack | 5 |
| 70011 | PROPEL™ sinus implant | 1 |
| 700115 | PROPEL™ sinus implant pack | 5 |