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Biosyn™ monofilament absorbable sutures are prepared from a synthetic polyester composed of glycolide, dioxanone, and trimethylene carbonate.
Biosyn™ sutures are indicated for use in general soft tissue approximation and/or ligation. The intended purpose of the suture is soft tissue approximation and/or ligation.
Biosyn™ sutures elicit a minimal acute inflammatory reaction in tissues, which is followed by gradual encapsulation of the suture by fibrous connective tissue. Progressive loss of tensile strength and eventual absorption of Biosyn™ sutures occurs by means of hydrolysis where the suture is broken down to glycolic acid, dioxanoic acid, propane diol, and carbon dioxide which are subsequently absorbed and metabolized by the body.
Absorption begins as a loss of tensile strength without appreciable loss of mass. Studies in indicate tensile strength averages for Biosyn™ sutures are approximately 75% of United States Pharmacopeia (USP) and European Pharmacopoeia (EP) minimum knot strength at two weeks and approximately 40% of USP and EP at three weeks post-implant. Absorption of Biosyn™ sutures is essentially complete between 90 and 110 days.
This suture, being absorbable, should not be used where extended approximation of tissue is required. Biosyn™ sutures should not be used on cardiovascular or neural tissues.
Find more information, including other available configurations, for Biosyn™ monofilament absorbable suture.
