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Addressing the opioid crisis

With minimally invasive treatment options for patients with VCFs

A 7-month retrospective claims analysis in Osteoporosis International shows balloon kyphoplasty (BKP) or vertebroplasty (VP) for vertebral compression fractures (VCF) reduced patient opioid use — and payer costs.1

A 7-month retrospective analysis compared opioid use and hospital visits in 8,845 patients before and after a BKP/VP procedure. Findings showed:

  • 48.7% of patients discontinued opioid use1    
  • 8.4% of patients reduced opioid use1
  • Average all-cause payer costs were reduced significantly1
Fifty-seven percent of patients (with any opioid use pre and/or post-surgery) decreased or discontinued opioid use after 7 months in follow-up.
Kyphon™ balloon kyphoplasty inserted into a collapsed vertebra

How balloon kyphoplasty works

BKP is a minimally invasive therapy backed by powerful clinical evidence

KyphonTM balloon kyphoplasty relieves pain from the vertebral compression fractures by using orthopaedic balloons to restore vertebral height and correct angular deformity.2 After reduction, the balloons are deflated and removed. The resulting cavity allows for a controlled deposition of Kyphon bone cement, which helps form an internal cast and stabilize the fracture.

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Risk statement


Kyphon™ Balloon Kyphoplasty is a minimally invasive procedure for the treatment of pathological fractures of the vertebral body due to osteoporosis, cancer, or benign lesion. Cancer includes multiple myeloma and metastatic lesions, including those arising from breast or lung cancer, or lymphoma. Benign lesions include hemangioma and giant cell tumor. The overall complication rate with the procedure has been demonstrated to be low.

Risks of acrylic bone cements include cement leakage, which may cause tissue damage, nerve or circulatory problems, and other serious adverse events, such as: cardiac arrest, cerebrovascular accident, myocardial infarction, pulmonary embolism, cardiac embolism. For complete information regarding indications for use, contraindications, warnings, precautions, adverse events, and methods of use, please reference the devices’ Instructions for Use included with the product.

  1. Ni W, Ricker C, Quinn M, Gasquet N, Janardhanan D, Gilligan CJ, Hirsch JA. Trends in opioid use following balloon kyphoplasty or vertebroplasty for the treatment of vertebral compression fractures. Osteoporos Int. 2021 Nov 2. doi: 10.1007/s00198-021- 06163-3. Epub ahead of print. PMID: 34729624.
  2. Boonen S, Van Meirhaeghe J, Bastian L, et al. Balloon kyphoplasty for the treatment of acute vertebral compression fractures: 2–year results from a randomized trial. J Bone Miner Res. 2011;26(7):1627-1637.
  3. Ong KL, Beall DP, Frohbergh M, Lau E, Hirsch JA. Were VCF patients at higher risk of mortality following the 2009 publication of the vertebroplasty “sham” trials? Osteoporos Int. 2018;29(2):375–383.
  4. Lange A, Kasperk C, Alvares L, Sauermann S, Braun S. Survival and cost comparison of kyphoplasty and percutaneous vertebroplasty using German claims data. Spine. 2014;39(4): 318–326.
  5. Edidin AA, Ong KL, Lau E, Kurtz SM. Morbidity and mortality after vertebral fractures: comparison of vertebral augmentation and non-operative management in the Medicare population. Spine. 2015;40(15):1228–1241.
  6. Edidin AA, Ong KL, Lau E, Kurtz SM. Mortality risk for operated and non-operated vertebral fracture patients in the Medicare population. J Bone Miner Res. 2011;26(7):1617-1626.
  7. McCullough BJ, Comstock BA, Deyo RA, Kreuter W, Jarvik JG. Major medical outcomes with spinal augmentation versus conservative therapy. JAMA Intern Med. 2013;173(16):1514-1521.
  8. Chen AT, Cohen DB, Skolasky RL. Impact of nonoperative treatment, vertebroplasty, and kyphoplasty on survival and morbidity after vertebral compression fracture in the Medicare population. J Bone Joint Surg Am. 2013;95(19):1729-1736.