Sac regression animation

You Can Address Aneurysm Sac Regression

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Why sac regression?

  • Sac regression is defined by the SVS as the reduction in maximum diameter of the aneurysm sac by > 5 mm.1
  • Latest clinical signals suggest aneurysm sac regression is associated with better long-term outcomes.2
Alert Indications, Safety, and Warnings

ADDRESSING SAC REGRESSION FACTORS WITH Endurant II/IIs

Endurant™ II/IIs AAA stent graft has demonstrated low type I and type II endoleaks in broad patient anatomies.3,4 With:

  • Accurate placement and controlled deployment5
  • Continuous seal, fixation, and graft conformability5
  • Durable hemostatic barrier and resistance against type II endoleaks6

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See the features and benefits of the Endurant II/IIs system in action.

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EVAR SUCCESS

Aneurysm sac regression ― a key indicator2 for EVAR success.

Dr. Ross Milner, Professor of Surgery, Codirector, Center for Aortic Diseases at The University of Chicago, discusses his thoughts on aneurysm sac regression post-EVAR.

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CLINICAL EVIDENCE  VQI Data

Latest data suggest aneurysm sac regression is associated with better long-term outcomes.2

Cohort that demonstrated sac regression at one year had significantly better outcomes than stable and expanding sac cohorts.

Graph depicting sac regression at 12 years compared to stable and expanding sac cohorts

Endurant data

Endurant demonstrates consistent and high sac regression rates across straightforward and complex anatomies.

Endurant Clinical Data
Graph depicting 5-year sac regression rate

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CHALLENGING EVAR PROCEDURE VIDEO CASE STUDY 

Dr. Ross Milner reviews the case
of a challenging EVAR patient
that resulted in a regressing
aneurysm sac.

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References

1

Ahn SS, Rutherford RB, Johnston KW, et al. Reporting standards for infrarenal endovascular abdominal aortic aneurysm repair. Ad Hoc Committee for Standardized Reporting Practices in Vascular Surgery of The Society for Vascular Surgery/International Society for Cardiovascular Surgery. J Vasc Surg. February 1997;25(2):405-410.

2

O’Donnell TFX, Deery SE, Boitano LT, et al. Aneurysm sac failure to regress after endovascular aneurysm repair is associated with lower long-term survival. J Vasc Surg. February 2019;69(2):414-422.

3

Singh MJ, Fairman R, Anain P, et al. Final Results of the Endurant Stent Graft System in the United States regulatory trial. J Vasc Surg. July 2016;64(1):55-62.

4

Teijink JAW, Power AH, Böckler D, et al. Editor's Choice - Five Year Outcomes of the Endurant Stent Graft for Endovascular Abdominal Aortic Aneurysm Repair in the ENGAGE Registry. Eur J Vasc Endovasc Surg. August 2019;58(2):175-181.

5

Medtronic data on file.

6

Wakefield TW, Shulkin BL, Fellows EP, Petry NA, Spaulding SA, Stanley JC. Platelet reactivity in human aortic grafts: a prospective, randomized midterm study of platelet adherence and release products in Dacron and polytetrafluoroethylene conduits. J Vasc Surg. February 1989;9(2):234-243.