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Resolute Onyx™ drug-eluting stent (DES) is a stent and balloon catheter delivery system designed to be placed inside a diseased coronary artery to keep the artery open so that blood can access the heart.
Contact UsResolute Onyx is the only DES proven safe and effective in high bleeding risk (HBR) patients with 1-month DAPT labeling, based on results from the Onyx ONE Clear Analysis.1
Single-wire Design — increasing conformability and apposition2
BioLinx Polymer — offering superior thromboresistance3
The Onyx ONE Month DAPT Program
Resolute Onyx DES is composed of a single wire strand formed into a continuous sinusoidal waveform, providing a fluid range of motion with greater flexibility and conformability when compared to laser-cut stents.4
Single-wire design
vs. Laser-cut design
Single wire design increases deliverability, flexibility, conformability, wall-apposition, and may reduce arterial injury and thrombus formation.2-4
Sinusoid formed wire
Helical wrap
Laser-fused
Higher is Better
Resolute Onyx DES is designed with rounded struts that may create a smooth passage for side branch access.4
Square Strut Cross-Section
Regular Cell Shape
Resolute Onyx DES
Irregular Cell Shape
Xience Sierra™* DES
The Resolute Onyx DES broad size matrix optimizes stent deployment and expansion.
5.75 mm maximum expansion for 4.50 and 5.00 mm sizes4‡
3.25 mm maximum expansion for 2.0 mm sizes4‡
Watch a short video to learn more about the BioLinx polymer.
The Resolute Onyx DES zotarolimus drug effectively inhibits neointimal growth while the exclusive, highly biocompatible BioLinx™ polymer contributes to minimal inflammation, low thrombotic risk5, as well as rapid, complete, and functional endothelial healing.4§
The 1-month OCT Study investigated early vessel healing in patients with complex coronary artery disease treated with Resolute Onyx DES.
92.3% Stent Coverage at 1 Month6
Strut Coverage
Log in to Medtronic Academy to browse a variety of Coronary education, training, and resources.
Log in to Medtronic AcademyResolute Onyx DES offers flexibility, conformability, deliverability, and enhanced visibility for complex percutaneous coronary intervention (PCI).‡
Learn More About Complex PCIView our latest product and therapy innovations, clinical evidence, and educational offerings for the interventional cardiology space.
View the latest from MedtronicMedtronic and Medtronic logo are trademarks of Medtronic. Third-party trademarks ("™*") belong to their respective owners. All other brands are trademarks of a Medtronic entity.
Including Resolute Integrity DES, part of the Medtronic DES portfolio
Resolute Onyx™ stents should not be expanded to a diameter beyond the maximum labeled diameter listed on the label per the IFU. Post-dilation required for overexpansion.
In porcine models.
Resolute Onyx DES, Instructions for Use.
Shown in independent assessment. Data on file at Medtronic.
Finn, et al. Assessment of acute thrombogenicity and albumin bindings in the Resolute Onyx Zotarolimus-eluting Coronary Stent System. Data presented at PCR 2019.
Based on bench test data on file at Medtronic. May not be indicative of clinical performance.
Silber S, Kirtane AJ, Belardi JA, et al. Lack of association between dual antiplatelet therapy use and stent thrombosis between 1 and 12 months following resolute zotarolimus-eluting stent implantation. Eur Heart J. August 1, 2014;35(29):1949-1956.
Roleder T, Kedhi E, Berta B, et al. Short-term stent coverage of second-generation zotarolimus-eluting durable polymer stents: Onyx one-month optical coherence tomography study. Adv Interv Cardiol. 2019;15(2):143-150.