OVERVIEW

EXPERIENCE THE AXIUMTM EFFECT

Experience proven softness, high-volume packing, minimal kickback, and exceptional detachment from the first to last coil.2

Axium™ Prime FRAME Detachable Coil

AXIUM™ PRIME FRAME: EXPERIENCE FLEXIBILITY AND STABILITY.3

1. COMPLETE PROXIMAL AND DISTAL ANCHOR LOOPS 

Closed loops are designed to reduce implant herniation.3

2. OPEN LOOP CONFIGURATION 

Open loops enhance confirmability to aneurysm irregularities.3

3. UNIFORM LOOP DISTRIBUTION AND DENSE NECK COVERAGE 

Successive loops change direction evenly distributing loops within the aneurysm and across the neck.3

Axium Prime with three features called out.

Progressively Larger Outer Diameters

A progressive outer diameter matched to the implant size optimizes stability and volume throughout the entire coil line.4

Chart showing that stability and volume increase with outer diameter size.

CHARACTERISTICS

  3D
Diameter (mm) 3–25
Length (cm) 6–50
Coil O.D. (in) 0.0115–0.0145
Vol. (mm³) 4.02–53.27

Axium™ Prime Soft and Extra Soft Detachable Coil

AXIUM PRIME™ SOFT: EXPERIENCE SMOOTHER FILLING5

SOFT IMPLANT
Thinner .0015” primary wire and precisely matched .0115” O.D. to fill more space.6

RANDOM BREAK COIL
Due to its winding pattern, when the coil encounters resistance, it can more easily deflect and seek out open spaces.6

AXIUM PRIME™ EXTRA SOFT: EXPERIENCE A SOFTER FINISH7

GREATER PACKING VOLUME
Larger .0108” O.D. provides more volume in a finishing coil.4,8

EXTRA SOFT IMPLANT
0.0013“ thinner primary wire leads to a softer coil paired with a precisely-matched O.D. to fill and finish more space.4,7.8-10

RANDOM BREAK COIL
Due to its winding pattern, when the coil encounters resistance it can more easily deflect and seek out open spaces.6

Closeup of the Axium Prime Soft.

AXIUM™ PRIME DETACHABLE  COIL SYSTEM EXTRA SOFT

Watch the product animation.

EXPERIENCE PROVEN SOFTNESS7 

When compared to the Target™ 360 Nano™ coil, the Axium™ Prime (Extra Soft) coil was 47% softer. The Axium™ Prime coil broke at less force, resulting in less force (g) exerted against the aneurysm wall.7*

Chart depicting pliability test results of the Axium Prime Extra Soft Coil vs. the Target 360 Nano Coil. Results show that the Axium Prime is 47% softer than Target 360 Nano, resulting in less force exerted against the aneursym wall.

For more information about this study, read the full summary.  

CHARACTERISTICS

  ES-3D ES-Helix SS-3D SS-Helix
Diameter (mm) 1–3.5 1–3 4–6 4–6
Length (cm) 2–10 1–10 6–20 6–20
Coil O.D. (in) 0.0108 0.0108 0.0115 0.0115
Vol. (mm³) 1.18–5.9 0.59–5.9 4.02–13.4 4.02–13.4

AXIUM™ MICROFX™ DETACHABLE COIL

Axium™ MicroFX™: EXPERIENCE RAPID FLOW REDUCTION11

Closeup of Axium MicroFX.

key benefits of Axium™ MicroFX™ coils

INTERLOCKED SURFACE AREA

Polymer fibers: Axium™ MicroFX™ coils contain PGLA or nylon microfilaments designed to impact flow reduction and accelerate thrombosis.12

LatticeFX™ Technology: LatticeFX™ technology provides an interlocked surface area or scaffold which orients cell adhesion and extracellular deposition.13

Axium MicroFX Product Photo
Enhanced thrombin generation with flamented coils compared to bare platinum coils.

ACCELERATED THROMBUS FORMATION12

Enhanced thrombin generation with filamented coils when compared to bare platinum coils and higher thrombogenicity may be beneficial in situations where rapid occlusion is needed.12

For more information, read the study summary

VESSEL OR FISTULA TAKE DOWN

An alternative to bare platinum coils for arteriovenous fistulae and other neurovascular abnormalities.14

Closeup of Axium coil within the vessel.

CHARACTERISTICS

  3D Helix
Diameter (mm) 2–18 2–10
Length (cm) 2–40 1–30
Coil O.D. (in) 0.0115–0.0145 0.0115–0.0135
Vol. (mm³) 1.34–42.62 0.67–27.7

Axium™ DETACHABLE COIL FAMILY

RELIABLE DETACHMENT

An instant mechanical detachment with 99.7% proven reliability15 and a manual break back-up detachment method.16

Flexible vs. Fixed Junctions

Ball and socket design allows the coil implant to move independently of the pusher in a 360° axial rotation resulting in less energy build up and microcatheter kickout for smooth coil delivery.6

Closeup of the Axium detachable system.

Axium™ Detachment System

Closeup of the Elecrolytic detachment system.

Electrolytic Detachment System

Compare our Axium™ products by softness, stability, and outer diameter size.

table

SPECIFICATIONS

INDICATIONS

The Axium™ and Axium™ Prime detachable coils are not intended for all patients and may not be the appropriate treatment for all clinical scenarios. Axium™ and Axium™ Prime detachable coils are intended for the endovascular embolization of intracranial aneurysms. Axium™ and Axium™ Prime detachable coils are also intended for the embolization of other neuro vascular abnormalities such as arteriovenous malformations and arteriovenous fistulae. Axium™ Prime Detachable Coil (Frame): The Axium™ Prime detachable coil system is indicated for the endovascular embolization of intracranial aneurysms and other neurovascular abnormalities, such as arteriovenous malformations and arteriovenous fistulae. The Axium™ Prime detachable coils are also indicated for arterial and venous embolizations in the peripheral vasculature.

Indications, Safety and Warnings

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1

Data on file. TRNV-14378A. 

2

Data on file. TR-NV12442. Based on bench test comparing average work number of Axium™ Prime extra soft coil versus Target® Nano™ coil. 20 units of each coil were tested. Bench testing is not indicative of clinical performance.;   Determined using formula for cylinder (volume = πr2 x length). Based on calculated k-factor values. ; . TR-NV12051; TR-NV12197; TR-NV10304 ;   RE00032057; TR-NV13164; TR09-218A.

3

Data on file. Top Level Drawing & RE00046057; TR-NV13163; MP1936B; 92566A.

4

Determined using formula for cylinder (volume = πr2 x length). Based on calculated k-factor values.

5

Data on file. TR-NV10836A. Based on bench test comparing average work number of Axium™ Prime coil (super soft) versus other competitor 4x8 fill coils. 15 units of Axium™ Prime coil and 9 units of the competitor coils were tested. Bench testing is not indicative of clinical performance.

6

Data on file. TR-NV12051; TR-NV12197; TR-NV10304.

7

Data on file. TR-NV12442. Based on bench test comparing average work number of Axium™ Prime extra soft coil versus Target® Nano™ coil. 20 units of each coil were tested. Bench testing is not indicative of clinical performance.

8

J.B. White, C.G.M. Ken, H.J. Cloft and D/F/ Kallmes. “Coils in a NutShell: A Review of Coil Physical Properties”. 2008.”

9

RE00032057; TR-NV13164; TR-NV13272.

10

Compared to Axium™ Prime (soft) coils.  

11

Fargen KM, Blackburn S, Carpenter JS, et al. J NeuroIntervent Surg Published Online First: doi:10.1136/neurintsurg-2013-01088.

12

Girdhar G, Read M, Sohn J, et al. In-vitro thrombogenicity assessment of polymer filament modified and native platinum embolic coils. J Neurol Sci. 2014;339:97-101.

13

Effect of fiber diameter and orientation on fibroblast morphology and proliferation on electrospin poly (D,L-lactic-co-gycolic acid) meshes. Biomaterials, 2006;27(33):5681-5688. Bashur, et.al.

14

70679-001 Axium™ 3D Detachable Coils Indications for Use.

15

RE00032057; TR09-218A.

16

RE00032057; TR-NV13164; TR-NV13272.

*

Based on bench testing, not indicative of clinical performance.