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Designed for presurgical embolization of brain arteriovenous malformations (bAVMs), Onyx™ liquid embolic system (LES) is a pre-mixed, radiopaque, injectable embolic fluid consisting of the following components: EVOH (ethylene vinyl-alcohol copolymer), DMSO (dimethyl-sulfoxide) and Ta (micronized tantalum powder).
see all bavm devicesDuring presurgical embolization of bAVMs, with the Onyx™ LES, the DMSO solvent dissipates into the blood and interstitial fluids, causing the EVOH copolymer and suspended tantalum to precipitate in situ into a spongy, coherent substance. The Onyx™ liquid embolic system begins to form a skin and solidifies over time from the outside to the inside.
Suspended micronized tantalum powder provides contrast visualization under fluoroscopy
Onyx™ cast reduces blood loss during neurosurgical removal of AVM
Its cohesive deposition and delivery1 provide a slow controlled Onyx™ injection, with the ability to stop when needed
The numerical term of Onyx™ LES describes its relative viscosity. Onyx™ LES is offered in 18 and 34 to provide options for controllable injections3.
The Apollo™ Onyx™ delivery microcatheter was expressly designed to access the neuro vasculature for the controlled selective infusion of the Onyx™ liquid embolic system (LES).4
The Marathon™ Flow Directed microcatheter is intended to access the peripheral and neuro vasculature for the controlled selective infusion of physician-specified therapeutic agents such as embolization materials and of diagnostic materials such as contrast media.5
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CONTACT USINDICATIONS
Onyx™ Liquid Embolic System is intended for presurgical embolization of brain arteriovenous malformations (bAVMs).
TR02-092, §5.10 & 6.4
TR98-076, §2, 6.2, 6.3, 6.6, & 7
TR02-092, §5.14, 5.15, 5.19.2, 6.8, 6.9
70556-001 03/14
70876-001 03/14