Designed for presurgical embolization of brain arteriovenous malformations (bAVMs), Onyx™ liquid embolic system (LES) is a pre-mixed, radiopaque, injectable embolic fluid consisting of the following components: EVOH (ethylene vinyl-alcohol copolymer), DMSO (dimethyl-sulfoxide) and TA (micronized tantalum powder).see all bavm devices
During presurgical embolization of bAVMs, with the OnyxTM LES system, the DMSO solvent dissipates into the blood and interstitial fluids, causing the EVOH copolymer and suspended tantalum to precipitate in situ into a spongy, coherent substance. The Onyx™ liquid embolic system begins to form a skin and solidifies over time from the outside to the inside.
The numerical term of Onyx™ LES describes its relative viscosity. OnyxTM LES is offered in 18 and 34 to provide options for controllable injections3.
The ApolloTM OnyxTM delivery microcatheter was expressly designed to access the neuro vasculature for the controlled selective infusion of the OnyxTM liquid embolic system (LES)4.
The MarathonTM flow directed microcatheter was designed for the infusion of therapeutic agents such as embolization materials5.
OnyxTM liquid embolic system is intended for presurgical embolization of brain arteriovenous malformations (bAVMs).
TR02-092, §5.10 & 6.4
TR98-076, §2, 6.2, 6.3, 6.6, & 7
TR02-092, §5.14, 5.15, 5.19.2, 6.8, 6.9